Key takeaways
Dexmethylphenidate (Focalin, Focalin XR) and dextroamphetamine (Dexedrine Spansule, ProCentra, Zenzedi) are both stimulant medications used to treat ADHD, but they have some differences. Dexmethylphenidate is typically taken as an immediate-release tablet twice a day or an extended-release capsule once a day, whereas dextroamphetamine can be taken as immediate-release tablets, oral liquid, or extended-release capsules, with dosing varying by age and condition. Dexmethylphenidate primarily affects norepinephrine and dopamine, while dextroamphetamine also impacts serotonin levels. Both medications can cause side effects like trouble sleeping and loss of appetite, but dextroamphetamine is also used to treat narcolepsy. Additionally, dextroamphetamine has a liquid form, which can be easier for some people to take. Both medications carry risks of misuse and dependence, so it's important to take them exactly as prescribed.
