Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Dexmethylphenidate (Focalin, Focalin XR) and methylphenidate extended-release (Concerta, among other brands) are both stimulant medications used to treat ADHD, but they have some differences. Dexmethylphenidate is available in both immediate-release and extended-release forms, while methylphenidate ER comes in various formulations, including tablets, capsules, chewable tablets, and liquid. Dexmethylphenidate is typically taken twice a day for the immediate-release form and once a day for the extended-release form, whereas methylphenidate ER is usually taken once daily. Both medications can cause side effects like trouble sleeping and loss of appetite, stomach upset or pain, and irritabiltiy or nervousness. Methylphenidate ER has a broader range of available forms, which might offer more flexibility depending on your needs. Both medications carry risks of misuse and dependence and are controlled substances. However, methylphenidate ER is often considered a first-choice option for ADHD and is available in many lower-cost generic forms.
Focalin (dexmethylphenidate)
Methylphenidate (Ritalin)
Focalin (dexmethylphenidate)
Methylphenidate (Ritalin)
Summary of Focalin vs. Ritalin
Summary for Stimulant
Prescription only
Dexmethylphenidate (Focalin, Focalin XR) is a stimulant medication that's used for treating attention deficit-hyperactivity disorder (ADHD) in adults and children. It's thought to work by balancing certain chemicals in your brain to help you focus. This medication is available as an immediate-release tablet that you take twice per day and an extended-release capsule you take once per day. Side effects can include stomach upset and nervousness. It can also cause withdrawal symptoms if it's suddenly stopped after long-term use. Focalin (dexmethylphenidate) is available as both a brand-name and lower-cost generic medication.
Summary for Stimulant
Prescription only
Methylphenidate hydrochloride (Ritalin) is a stimulant medication that's used for treating attention deficit-hyperactivity disorder (ADHD) and narcolepsy (daytime sleepiness) in adults and children ages 6 years and older. It works by raising the levels of certain chemicals in your brain to keep you focused and awake. The dosage is typically 2 to 3 times per day because it's an immediate-release form of methylphenidate. Side effects of this medication include low appetite, nervousness, and trouble sleeping.