Key takeaways
Dexmethylphenidate (Focalin, Focalin XR) and Guanfacine ER (Intuniv) are both used to treat ADHD, but they work in different ways and have different side effects. Dexmethylphenidate is a stimulant that helps balance chemicals in your brain to improve focus and attention. It can cause side effects like stomach upset, nervousness, and trouble sleeping. It is a controlled substance, meaning it has a risk of misuse and dependence. On the other hand, Guanfacine ER is a non-stimulant that works by lowering norepinephrine levels in certain parts of the brain. It can cause sleepiness and tiredness, and it is not a controlled substance, so there's no concern for abuse or dependence. Guanfacine ER is only approved for children and adolescents, while Dexmethylphenidate can be used by both adults and children. Additionally, Dexmethylphenidate is available in both immediate-release and extended-release forms, whereas Guanfacine ER is only available in an extended-release form.
