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Compare Evekeo vs. Adderall XR

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Amphetamine sulfate (brands: Evekeo, Adzenys XR ODT) and Adderall XR (generic name: dextroamphetamine/amphetamine salts extended release) are both stimulant medications used to treat attention deficit hyperactivity disorder (ADHD). While both medications are effective for ADHD, they have some differences. Amphetamine sulfate is available in various forms, including immediate-release tablets, extended-release tablets, orally disintegrating tablets, and oral liquids, whereas Adderall XR is only available in extended-release capsules. Amphetamine sulfate can also be used for narcolepsy and short-term obesity treatment, but Adderall XR is only approved for ADHD. Adderall XR is typically taken once a day and lasts up to 12 hours, while the duration of amphetamine sulfate's effects depends on the form taken. Both medications have a risk of misuse and dependence, but Adderall XR is available as a lower-cost generic, whereas some forms of amphetamine sulfate are only available as brand-name medications. Additionally, Adderall XR can be used in children as young as 6 years old, while Mydayis, another form of Adderall XR, is only approved for those 13 and older.

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