Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Provigil (modafinil) and Ritalin (methylphenidate) are both stimulant medications. Both medications are approved to treat extreme sleepiness from narcolepsy. Provigil is also approved to treat sleepiness from obstructive sleep apnea and shift work disorder. And Ritalin is approved to treat ADHD (attention deficit-hyperactivity disorder). Provigil is taken once a day for narcolepsy, while Ritalin is usually taken a few times a day. In general, Provigil is a first-choice medication for narcolepsy. While both medications are controlled substances, Provigil is considered less likely to cause dependence and misuse than Adderall.
Modafinil (Provigil)
Methylphenidate (Ritalin)
Modafinil (Provigil)
Methylphenidate (Ritalin)
Summary of Provigil vs. Ritalin
Summary for Wakefulness-promoting agent
Prescription only
Modafinil (Provigil) is a prescription medication used to improve wakefulness in people who have extreme sleepiness due to narcolepsy, obstructive sleep apnea, or shift work disorder. It's considered a controlled substance since this medication has a potential to cause misuse. You should avoid alcohol while taking modafinil (Provigil), as well as certain other medications to avoid any serious interactions and side effects. Common side effects of modafinil (Provigil), however, include headache and nausea.
Summary for Stimulant
Prescription only
Methylphenidate hydrochloride (Ritalin) is a stimulant medication that's used for treating attention deficit-hyperactivity disorder (ADHD) and narcolepsy (daytime sleepiness) in adults and children ages 6 years and older. It works by raising the levels of certain chemicals in your brain to keep you focused and awake. The dosage is typically 2 to 3 times per day because it's an immediate-release form of methylphenidate. Side effects of this medication include low appetite, nervousness, and trouble sleeping.