Compare
Medrol vs. Provigil

Methylprednisolone (Medrol) is a steroid medication used to treat different medical conditions with an overactive immune system. It's typically available by prescription as tablets. And it sometimes comes in a dose pack, which helps you organize the tablets into specific days and times. If you use methylprednisolone (Medrol) for a long time, it might cause certain side effects, such as weight gain, skin thinning, and high blood sugar.

Methylprednisolone (Medrol) is used for many different medical conditions, including:

• Conditions affecting certain hormones (e.g., low adrenal hormones)
• Joint conditions (e.g., rheumatoid arthritis)
• Lupus
• Skin conditions (e.g., Stevens-Johnson syndrome)
• Allergic reactions
• Eye inflammation
• Lung problems
• Conditions related to blood cells
• Cancer of blood cells (e.g., leukemia)
• Gut conditions (e.g., ulcerative colitis)
• Multiple sclerosis

• Swelling
• Muscle weakness
• Stomach pain
• Bloating
• Increased appetite
• Trouble sleeping
• Weight gain
• Dizziness

• New or worsened infection
• Mood and behavior changes
• Reduced adrenal gland function
• Changes in heart and kidney function
• Stomach problems
• Bone problems with long-term use
• Eye problems with long-term use
• High blood sugar

Modafinil (Provigil) helps improve wakefulness in adults with narcolepsy, obstructive sleep apnea, or shift work disorder. This wake-promoting medication comes as a tablet that’s taken by mouth. For adults with narcolepsy or sleep apnea, you take a dosage once daily in the morning. And for those with shift work disorder, you take your dosage 1 hour before the start of your work shift. Common side effects include headache and nausea. Modafinil (Provigil) is a controlled substance because of its potential for misuse.

• Improve wakefulness in adults with narcolepsy, obstructive sleep apnea, or shift work disorder

• Headache (34%)
• Nausea (11%)
• Feeling nervous (7%)
• Runny nose (7%)
• Back pain (6%)
• Diarrhea (6%)
• Anxiety (5%)
• Dizziness (5%)
• Indigestion (5%)
• Trouble sleeping (5%)

• Serious allergic reactions
• Serious rash and skin reactions
• Sleepiness and trouble focusing, thinking, and reacting
• Unusual changes in mood and behavior
• Heart problems
• Changes in blood pressure and heart rate