methylprednisolone

Using methylprednisolone (Medrol) long term can raise your risk of getting an infection or hide signs of an infection. These infections include serious fungal, viral (e.g., chicken pox, measles), or bacterial (e.g, tuberculosis or TB) infections. Avoid close contact with anyone who had a history of these serious infections during treatment with methylprednisolone (Medrol). If you have had TB or parasitic (worm) infections in the past, let your provider know so they can closely monitor you for symptoms and make sure these infections don't come back. In addition, talk to your provider first before getting any vaccination. Live vaccines might not be safe for you since they can sometimes raise your risk of an infection during treatment with high doses of methylprednisolone (Medrol).

Methylprednisolone (Medrol) can cause changes in your mood or behavior. Tell your provider right away if you feel depressed, have mood swings, trouble sleeping, anxiety, or hallucinations (hearing or seeing things that aren't there) while taking this medication.

In some rare cases, using methylprednisolone (Medrol) for a long time can cause a medical condition called adrenal suppression. This is when your adrenal glands stop making your own natural hormones as your body gets used to methylprednisolone (Medrol). If you suddenly stop the medication, it can be dangerous to your body. In adults, symptoms of withdrawal include fever, joint or muscle pain, and low energy. In children, symptoms often include stunted growth, weight gain, and headaches. To prevent adrenal suppression from happening, your provider will prescribe the lowest possible dose of methylprednisolone (Medrol) that works well for you for the shortest amount of time. If you need to use methylprednisolone (Medrol) for a long period of time, your provider may ask you to do some lab work to test how well your adrenal gland works. Let your provider know if you have symptoms of withdrawal. Don't suddenly stop using methylprednisolone (Medrol) without talking to your provider first.

Methylprednisolone (Medrol) can cause changes in your fluids and electrolytes (e.g., sodium, potassium, and calcium). This can result in high blood pressure, swelling, and kidney problems. In addition, some studies suggest that methylprednisolone (Medrol) can damage the heart if used after a recent heart attack. If you have a history of heart failure, heart attack, high blood pressure, or kidney problems, let your provider know before using this medication.

Taking methylprednisolone (Medrol) raises the risk of stomach damage, leading to certain problems, like stomach irritation, and more seriously, ulcers and bleeding. Your risk is higher if you have a history of stomach problems or if you're taking other medications that can damage your stomach, such as nonsteroidal anti-inflammatory drugs (NSAIDs). You should avoid drinking alcohol while taking this medication because it can worsen stomach irritation. Get medical attention right away if you have stomach pain that doesn't go away or you get bloody or dark stools. These can be signs of a serious stomach problem.

Long-term use of methylprednisolone (Medrol) can lower calcium absorption and weaken your bone. Over time, this will cause or worsen osteoporosis in adults or slow down growth in children. If you've had bone fractures before or have osteoporosis (weak bones), talk to your provider about your risk before using this medication.

Using methylprednisolone (Medrol) for a long period of time can lead to greater risk of cataracts, glaucoma, and certain eye infections. Tell your provider if you currently have an eye infection or have had a viral eye infection (herpes keratitis) in the past. If you experience blurry vision, eye pain, or any vision changes during treatment with this medication, let your provider know right away. You might need to get regular eye exams during long-term treatment with methylprednisolone (Medrol).