Key takeaways
Lidocaine 5% patch (Lidoderm) and hydrocortisone cream (Locoid, Pandel) are both used to treat skin-related conditions, but they belong to different medication classes. Lidoderm is a local anesthetic used to numb nerve pain from shingles, while hydrocortisone is a corticosteroid that reduces inflammation to treat skin conditions such as eczema and psoriasis. Lidoderm is a prescription-only patch that's applied once daily for up to 12 hours in a 24-hour period. Hydrocortisone cream is available both over-the-counter and by prescription, with application frequency varying by formulation. Lidoderm patches can cause skin irritation and have potential interactions with other medications, while hydrocortisone may lead to skin thinning and irritation if used long-term. Both medications should be used as directed to minimize side effects and interactions.
