Key takeaways
Pramoxine (Dermend Moisturizing Anti-Itch) and lidocaine 5% patch (Lidoderm) are both local anesthetics used to relieve pain and itching, but they differ in several ways. Pramoxine is an over-the-counter topical medication used for minor burns, insect bites, rashes, and hemorrhoids. Lidoderm is a prescription-only patch used primarily for nerve pain caused by shingles, known as postherpetic neuralgia. While pramoxine is applied as a cream, lotion, or foam multiple times a day, Lidoderm patches are applied once daily for up to 12 hours in.a 24-hour period. Common side effects of pramoxine include skin redness and irritation, whereas Lidoderm can cause skin irritation, numbness, and more serious reactions if absorbed in excess.
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