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Dermend Moisturizing Anti-Itch

pramoxine
Used for Itching
Used for Itching

Pramoxine is a topical medication used on the skin to relieve pain and itching from minor burns, scrapes, insect bites, hemorrhoids, and rashes. It's found in many over-the-counter, anti-itch products.

Reviewed by:
reviewer
Shifali Patel, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on February 23, 2022
BasicsSide effectsPros & consPharmacist tipsFAQsDosageCostAlternativesPricesMedicare
basics-icon

What is Pramoxine?

What is Pramoxine used for?

Relief of pain and itching from:

  • Minor burns

  • Sunburn

  • Minor cuts or scrapes

  • Insect bites

  • Rash from poison ivy, poison oak, or poison sumac

  • Skin irritation

  • Hemorrhoids

How Pramoxine works

Pramoxine is a local anesthetic. It blocks pain signals in your nerves where it's applied. This causes numbness and lowers pain to help treat itchy or irritated skin.

Are you looking for information on Pramosone, Proctofoam HC (hydrocortisone / pramoxine) instead?

Drug Facts

Common BrandsCeraVe Itch Relief, DerMend Moisturizing Anti-Itch, Sarna Sensitive, Proctofoam NS
Drug ClassLocal anesthetic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityOver-the-counter
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Avg retail price
$32.15(save 82.88%)
GoodRx discount
$5.51
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What are the side effects of Pramoxine?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Source: DailyMed

pros-and-cons

Pros and cons of Pramoxine

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Pros

Available in many forms, such as a cream, lotion, and foam

Works well to treat itchy skin related to skin conditions such as eczema and sunburn

Doesn't contain any steroids, unlike common anti-itch creams, such as hydrocortisone (Locoid)

Available over the counter

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Cons

Need to use it multiple times per day

Can cause unpleasant side effects, such as skin irritation or swelling

Not recommended for use longer than 1 week

Not known if safe to use during pregnancy

pharmacist-tips

Pharmacist tips for Pramoxine

pharmacist

  • Before using pramoxine, clean and rinse the affected area of your skin with a mild soap and warm water. After patting the area dry, apply the necessary amount of medication directly to the affected area(s).

    • If you're using the foam for hemorrhoids, make sure to shake it well before using it. Pump the medication onto a clean tissue, and use this tissue to apply it to the affected area(s). Don't insert your finger or any part of the container into your rectum.

      • After you're done applying the medication, wash your hands well to prevent the medication from coming into contact with other parts of your body.

        • Pramoxine should only be used on the outer layers of your skin. Avoid using it in or around your eyes, as this can cause burning or irritation.

          • Pramoxine contains many other ingredients and chemicals, such as alcohol and petrolatum. Carefully read the labeling on your product to make sure you're not allergic or sensitive to any of the listed ingredients. If you're unsure, ask your pharmacist or healthcare provider.

            • If your symptoms don't go away after 7 days, they clear up and come back again within a few days, you develop any redness, irritation, swelling, or pain, or you experience rectal bleeding (if using for hemorrhoids), stop using pramoxine and contact your provider.

              • Store pramoxine at room temperature in its original container and away from children at all times. If your child accidentally swallows pramoxine, get emergency medical help or call your local poison control center at 1-800-222-1222 right away.

                faqs

                Frequently asked questions about Pramoxine

                How often can I use pramoxine in a day?
                This depends on what condition you're using pramoxine for. You shouldn't use pramoxine more than 3 to 4 times per day for sunburn, insect bites, rash, skin irritation, or minor burns, cuts, or scrapes. For hemorrhoids, you can use it up to 5 times daily. Using pramoxine more often than recommended can cause greater side effects, such as skin irritation.
                How long do I use pramoxine?
                Don't use pramoxine for longer than 7 days. If your symptoms last longer than 1 week, stop using pramoxine and let your healthcare provider know. If your symptoms go away and come back again within a few days of stopping the medication, let your provider know as well. In these situations, you might need to use a different medication to treat your symptoms.
                Can I use pramoxine for any kind of skin irritation or damage?
                Pramoxine can only be used for minor burns, cuts or scrapes, insect bites, rashes, and skin irritation. If you have any serious skin damage, such as deep, puncture wounds, animal bites, or serious burns, contact your provider or get medical help right away. You'll need to get appropriate care for these types of skin damage.
                Is pramoxine safe to use in children?
                Pramoxine is safe to use in children ages 2 years and older for sunburn, insect bites, rash, skin irritation, and minor burns, cuts, or scrapes. Pramoxine can be used over the counter in children 12 years and older for the treatment of hemorrhoids. There aren't any studies looking at the safety of using pramoxine in younger children for these conditions. Ask your child's healthcare provider about the best treatment options if your child is under these age limits for their specific condition.
                Is pramoxine safe to use while pregnant or breastfeeding?
                There isn't enough information to know if pramoxine is safe to use while pregnant or breastfeeding. It's unknown if the medication can cause harm to your unborn or breastfed baby. For your baby's safety, discuss the risks and benefits of using pramoxine with your healthcare provider first.
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                dosage

                Pramoxine dosage forms

                The average cost for 1 bottle of 237ml of 1% of Pramoxine is $5.51 with a free GoodRx coupon. This is 82.88% off the average retail price of $32.15.
                bottle of lotion
                Bottle of lotion
                DosageQuantityPrice as low asPrice per unit
                237ml of 1%1 bottle$5.51$5.51

                Typical dosing for Pramoxine

                Sunburn, insect bites, rash, skin irritation, or minor burns, cuts, or scrapes

                • Adults and children 2 years or older: Apply to the affected area(s) of skin 3 to 4 times per day.

                • Children 1 year and younger: Ask your child's provider.

                Hemorrhoids

                • Adults and children 12 years or older: Apply to the affected area up to 5 times per day.

                • Children 11 years and younger: Ask your child's provider.

                drug-cost

                How much does Pramoxine cost?

                To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                Dermend Moisturizing Anti-Itch (brand)
                GoodRx lowest price

                $5.51

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                alternatives

                What are alternatives to Pramoxine?

                There are a number of medications that your doctor can prescribe in place of Pramoxine. Compare a few possible alternatives below.
                Pramoxine
                Used for:

                Relief of pain and itching from:

                • Minor burns

                • Sunburn

                • Minor cuts or scrapes

                • Insect bites

                • Rash from poison ivy, poison oak, or poison sumac

                • Skin irritation

                • Hemorrhoids

                $5.51 Lowest GoodRx priceView Prices
                Topical lidocaine
                Used for:

                • Minor burns

                • Sunburns

                • Minor cuts

                • Scrapes

                • Insect bites

                • Minor skin irritations

                • Joint and muscle pain

                • Hemorrhoids and other irritations in the anal area

                • Tattoos, piercings, microblading, and other skin procedures

                $18.02 Lowest GoodRx priceView Prices
                Analpram HC (hydrocortisone / pramoxine)
                Used for:

                • Itching and inflammation from certain skin conditions, like psoriasis

                $26.24 Lowest GoodRx priceView Prices

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