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Compare Aspercreme Original vs. Lidoderm

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Trolamine salicylate (Aspercreme Original) and lidocaine (Lidoderm) are both topical medications used to relieve pain, but they belong to different medication classes. Trolamine salicylate is a topical non-steroidal anti-inflammatory drug (NSAID) used for minor aches and pains like arthritis and muscle strains. Lidocaine viscous is a local anesthetic used for temporary relief of pain or discomfort from cuts, burns, and other skin conditions, as well as joint or muscle pain. Trolamine salicylate is available over-the-counter in forms like cream, spray, and foam, while lidocaine comes as a patch and is avaiable as a prescription or an OTC. Trolamine salicylate is applied up to four times a day, whereas lidocaine is applied once daily for a 12-hour period. Both medications can cause skin irritation. Lidocaine can also cause a mild burning sensation where you applied the patch.

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