Key takeaways
Dexamethasone (Hemady) and hydrocortisone (Cortef) are both corticosteroids used to treat various inflammatory and autoimmune conditions. Dexamethasone is a long-acting corticosteroid available in oral, intravenous (IV) injection, and liquid forms, while Cortef is a low-strength corticosteroid available only as an oral tablet. Dexamethasone is stronger than hydrocortisone and can treat a wider range of conditions, including multiple myeloma (Hemady brand only) and certain blood-related conditions. In contrast, hydrocortisone is less potent and might not be strong enough for severe conditions. Both medications can cause side effects like trouble sleeping, weight gain, and stomach issues, but dexamethasone has a higher risk of causing long-term problems with bones, skin, and eyes. Dexamethasone adn Cotef are both available in generic forms, making them more affordable. Both medications require careful tapering to avoid withdrawal symptoms and should be taken with food to minimize stomach irritation.
