Anti-epileptics are used to control seizures to treat epilepsy and trigeminal neuralgia. They work by reducing irregular brain impulses in the brain that cause seizures and pain.

Why are
Anti-epileptics
prescribed?

How is this chart calculated?

How we make this chart

This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition.

Prices for Popular Anti-epileptics

Popularity Brand Name (Generic Name) GoodRx Fair Price Price Trend
Neurontin
(gabapentin)
12
See Prices
Gabapentin (Neurontin) is an inexpensive drug used to control partial seizures in adults with epilepsy. It is also used to treat certain types of nerve pain. This drug is more popular than comparable drugs. It is available in generic and brand versions. Generic gabapentin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Lamictal
(lamotrigine)
10
See Prices
Lamotrigine (Lamictal) is an inexpensive drug used to control seizures in adults and children with epilepsy and Lennox-Gastaut syndrome. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Topamax
(topiramate)
9
See Prices
Topiramate (Topamax) is an inexpensive drug used to treat seizures in adults or children with epilepsy. It is also used for the prevention of migraine headaches. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic topiramate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Keppra
(levetiracetam)
15
See Prices
Levetiracetam (Keppra) is a moderately priced drug used with other medications to treat certain types of seizures. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. Generic levetiracetam is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Lyrica
353
See Prices
Lyrica (pregabalin) is an expensive drug used to treat nerve pain from diabetes, shingles, spinal cord injury, and fibromyalgia. It is also used to control seizures in epilepsy. It is slightly less popular than comparable drugs. A generic version of Lyrica may become available in 2019. Lyrica is covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can still help offset the cost.
Depakote
(divalproex)
17
See Prices
Divalproex (Depakote) is a moderately priced drug used to prevent seizures caused by some forms of epilepsy. It is also used to treat bipolar mania and to prevent migraine headaches. This drug is slightly less popular than other comparable drugs. It is available in brand and generic versions. Generic divalproex is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Trileptal
(oxcarbazepine)
16
See Prices
Oxcarbazepine (Trileptal) is a moderately priced drug used to treat people with epilepsy. It helps prevent partial seizures. This drug is less popular than other comparable drugs. It is available in brand and generic versions. Generic oxcarbazepine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Dilantin
(phenytoin)
19
See Prices
Phenytoin (Dilantin) is a moderately priced drug used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic phenytoin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Depakote ER
(divalproex er)
75
See Prices
Divalproex ER (Depakote ER) is an expensive drug used to prevent seizures caused by some forms of epilepsy. It is also used to treat bipolar mania and to prevent migraine headaches. This drug is slightly less popular than other comparable drugs. It is available in brand and generic versions. Generic divalproex er is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Tegretol
(carbamazepine, epitol)
30
See Prices
Carbamazepine (Tegretol, epitol) is a moderately priced drug used to control seizures caused by certain types of epilepsy. This medicine is also used to treat nerve related pain. This drug is less popular than comparable drugs. It is available in multiple brand and generic versions. Generic carbamazepine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Phenytek
(phenytoin)
19
See Prices
Phenytoin (Dilantin) is a moderately priced drug used to control seizures in certain types of epilepsy. It is also used to prevent seizures during or after surgery. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic phenytoin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Zonegran
(zonisamide)
16
See Prices
Zonisamide (Zonegran) is a moderately priced drug used to control partial seizures in adults with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic zonisamide is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Tegretol XR
(carbamazepine er)
62
See Prices
Carbamazepine ER (Tegretol XR) is a moderately priced drug used to control seizures caused by certain types of epilepsy. This medicine is also used to treat nerve related pain. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic carbamazepine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Carbatrol
(carbamazepine er)
62
See Prices
Carbamazepine ER (Tegretol XR) is a moderately priced drug used to control seizures caused by certain types of epilepsy. This medicine is also used to treat nerve related pain. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic carbamazepine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Mysoline
(primidone)
10
See Prices
Primidone (Mysoline) is a moderately priced drug used to control seizures in certain types of epilepsy. It is not for use in absence (petit mal) seizures. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic primidone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Vimpat
737
See Prices
Lacosamide (Vimpat) is an expensive drug used to control seizures caused by certain types of epilepsy. This drug is less popular than comparable drugs. A generic version of Vimpat may become available in 2022. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Keppra XR
(levetiracetam er)
29
See Prices
Levetiracetam ER (Keppra XR) is an expensive drug used with other medicines to treat certain types of seizures. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic levetiracetam ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Lamictal XR
(lamotrigine er)
208
See Prices
Lamotrigine ER (Lamictal XR) is an expensive drug used to control seizures in adults and children with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic lamotrigine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Depakene
(valproic acid)
26
See Prices
Valproic acid (Depakene) is a moderately priced drug used to treat certain types of seizures in patients with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic valproic acid is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Trokendi XR
585
See Prices
Topiramate (Trokendi XR) is an expensive drug used to treat seizures in adults or children with epilepsy. This drug is less popular than comparable drugs. There are currently no generic alternatives for Trokendi XR. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Zarontin
(ethosuximide)
111
See Prices
Ethosuximide (Zarontin) is an expensive drug used to control seizures in certain types of epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic form. Generic zarontin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Gralise
596
See Prices
Gabapentin (Gralise) is an expensive drug used to treat certain types of nerve pain. This drug is less popular than comparable drugs. A generic version of Gralise may become available in 2024. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Felbatol
(felbamate)
293
See Prices
Felbamate (Felbatol) is an expensive drug used to control seizures in certain types of epilepsy. This medicine is only for people who have not responded to other therapy. This drug is less popular than comparable drugs. It is available in generic and brand versions. Generic Felbamate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Qudexy XR
(topiramate er)
289
See Prices
Topiramate ER (Qudexy XR) is an expensive drug used to treat epilepsy and Lennox Gastaut syndrome. This drug is less popular than comparable drugs. It is available in generic and brand versions. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Horizant
339
See Prices
Gabapentin (Horizant) is an expensive drug used to treat Restless Legs Syndrome and certain types of nerve pain. This drug is less popular than comparable drugs. There are currently no generic alternatives for Horizant. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Banzel
2,184
See Prices
Rufinamide (Banzel) is an expensive drug used to control seizures caused by a certain type of epilepsy called Lennox-Gastaut syndrome. This drug is less popular than comparable drugs. A generic version of Banzel may become available in 2022. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Oxtellar XR
394
See Prices
Oxcarbazepine (Oxtellar XR) is an expensive drug used to treat people with epilepsy. It helps prevent partial seizures. This drug is less popular than comparable drugs. There are currently no generic alternatives to Oxtellar XR. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Aptiom
769
See Prices
Eslicarbazepine (Aptiom) is an expensive drug used to treat people with epilepsy. It helps prevent partial seizures. This drug is less popular than comparable drugs. There are currently no generic alternatives to Aptiom. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Briviact
919
See Prices
Brivaracetam (Briviact) is an expensive drug used with other medications to control seizures in certain types of epilepsy. This drug is less popular than comparable drugs. There are currently no generic alternatives to Briviact. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gabitril
(tiagabine)
148
See Prices
Tiagabine (Gabitril) is an expensive drug used to control partial seizures in adults and children with epilepsy. This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic tiagabine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Equetro
207
See Prices
Carbamazepine (Equetro) is an expensive drug used to treat mixed and manic episodes of bipolar disorder. This drug is less popular than comparable drugs. There are currently no generic alternatives to Equetro. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Celontin
56
See Prices
Methsuximide (Celontin) is a moderately priced drug used to control seizures in certain types of epilepsy. This drug is less popular than comparable drugs. There are currently no generic alternatives to Celontin. It is currently covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Sabril
19,862
See Prices
Vigabatrin (Sabril) is an expensive drug used to control seizures caused by certain types of epilepsy. This drug is less popular than comparable drug. There are currently no generic alternatives to Sabril. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Spritam
450
See Prices
Levetiracetam (Spritam) is an expensive drug used with other medications to treat certain types of seizures. This drug is less popular than comparable drugs. There are currently no generic alternatives to Spritam. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Lacosamide
N/A N/A See Prices
Carnexiv
N/A N/A See Prices
Stavzor
286
See Prices
Peganone
47
See Prices
Ethotoin (Peganone) is a moderately priced drug used to control seizures in certain types of epilepsy. This drug is less popular than comparable drugs. There are currently no generic alternatives to Peganone. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Elepsia XR
N/A N/A See Prices

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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