Diabetes Type 2 Medications

Popular Diabetes Type 2 Drugs

Popularity Drug Name Drug Class Price Price Trend
Biguanides 5
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Metformin (Glucophage) is an inexpensive drug used to treat high blood sugar levels caused by type 2 diabetes. It is is more popular than comparable drugs. It is available in both brand and generic versions. Generic metformin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Biguanides 9
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Metformin ER (Glucophage XR) is an inexpensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic metformin ER is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
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Insulins 385
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Lantus (insulin glargine) is a long-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. Lantus is more popular than comparable drugs. There are currently no generic alternatives for any insulin, but there is an alternative insulin with the same active ingredient as Lantus. Insulins are expensive, but the manufacturer provides coupons to help offset the cost for eligible users. Lantus is covered by most Medicare and insurance plans.
Sulfonylureas 8
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GLIPIZIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
Sulfonylureas 14
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GLIMEPIRIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body use insulin better.
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Insulins 510
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Humalog (insulin lispro) is an expensive, short-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. It is slightly more popular than comparable drugs. There are currently no generic alternatives for any insulin brand. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Sulfonylureas 14
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GLIPIZIDE helps to treat type 2 diabetes. It is combined with diet and exercise. The medicine helps your body to use insulin better.
Glitazones 12
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PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 538
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Novolog (insulin aspart) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly more popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptins 397
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Sitagliptin (Januvia) is an expensive drug used to treat type 2 diabetes. It helps to control blood sugar. This drug is more popular than comparable drugs. A generic version of Januvia may become available in 2022. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Medical Supplies and Devices 155 N/A See Prices
Test Strips 155 N/A See Prices
Sulfonylureas 15
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GLYBURIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
SGLT2 Inhibitors 439
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Canagliflozin (Invokana) is an expensive drug used to treat type 2 diabetes. It helps to control blood sugar. This drug is more popular than comparable drugs. There are currently no generic alternatives to Invokana. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 761
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Liraglutide (Victoza) is an expensive drug used to improve blood sugar control in adults with type 2 diabetes. This drug is more popular than comparable drugs. There are currently no generic alternatives to Victoza. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Insulins 409
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Levemir (insulin detemir) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Insulins 450
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Humulin N (insulin human) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptins 363
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Linagliptin helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 347
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Toujeo (insulin glargine) is long-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. Toujeo is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand. Less expensive biosimilar versions may be available in the future, but there are none approved for Toujeo at this time. Insulins are expensive, but the manufacturer provides coupons to help offset the cost for eligible users. Toujeo is covered by most Medicare and insurance plans.
Gliptin / Biguanide Combinations 393
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Metformin/sitagliptin (Janumet) is an expensive drug used to treat type 2 diabetes. This medicine lowers blood sugar. This drug is more popular than comparable drugs. A generic form of Janumet may become available in 2027. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 641
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DULAGLUTIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
Insulins 148
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Humulin R (insulin human) is an expensive drug used to control blood sugar levels in diabetes mellitus including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
SGLT2 Inhibitors 436
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EMPAGLIFLOZIN helps to treat type 2 diabetes. It helps to control blood sugar. This drug may also reduce the risk of heart attack or stroke if you have type 2 diabetes and risk factors for heart disease. Treatment is combined with diet and exercise.
Insulins 450
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Humulin 70/30 (insulin human) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Bayer Contour test strips are used to measure glucose in the blood.
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Bayer Contour test strips are used to measure glucose in the blood.
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Gliptin / Biguanide Combinations 393
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METFORMIN; SITAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Sulfonylurea / Biguanide Combinations 12
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GLYBURIDE; METFORMIN to treat type 2 diabetes. It is combined with a diet and exercise. This medicine helps your body to use insulin better.
Sulfonylurea / Biguanide Combinations 28
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GLIPIZIDE; METFORMIN helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body to use insulin better.
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Insulins 145
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Novolin 70/30 (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
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Insulins 538
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Novolog 70/30 (insulin aspart) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
SGLT2 Inhibitors 443
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DAPAGLIFLOZIN helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Biguanides 472
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Metformin ER (Fortamet) is an expensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Insulins 506
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Humalog 75/25 (insulin lispro) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Insulins 145
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Novolin N (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Insulins 452
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Tresiba (insulin degludec) is an expensive drug used to lower the amount of sugar in your blood. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Bile Acid Sequestrants 580
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Colesevelam (Welchol) is an expensive drug used to lower in patients who are at risk of heart disease. This drug is more popular than comparable drugs. There are currently no generic alternatives to Welchol. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 628
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EXENATIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
Gliptins 173
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ALOGLIPTIN (al oh glip tin) helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 323
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Basaglar (insulin glargine) is an expensive, long-acting type of insulin. It is the first biosimilar insulin used to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. It is more popular than comparable drugs. There are currently no generic alternatives for any insulin brand, but Basaglar is a biosimilar to Lantus, one of the most popular long-acting insulins. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Glinides 38
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REPAGLINIDE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 145
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Novolin R (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
SGLT2 Inhibitor / Biguanide Combinations 439
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CANAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
GLP-1 Agonists 492
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ALBIGLUTIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
Glinides 69
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NATEGLINIDE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Gliptin / Biguanide Combinations 387
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METFORMIN; LINAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
SGLT2 Inhibitor / Gliptin Combinations 537
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EMPAGLIFLOZIN; LINAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Gliptins 397
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SAXAGLIPTIN helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
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Insulins 498
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Apidra (insulin glulisine) is a fast-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. Apidra is less popular than comparable drugs. There are currently no generic options for any insulin brand. Less expensive biosimilar versions may be available in the future, but there are none approved for Apidra at this time. Insulins are expensive, but the manufacturer provides coupons to help offset the cost for eligible users. Apidra is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can still help offset the cost.
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TRUEtrack Test Strips are compatible with the TRUEtrack Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
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TRUEtrack Test Strips are compatible with the TRUEtrack Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
GLP-1 Agonists 684
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Exenatide (Byetta) is an expensive drug used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines. This drug is less popular than comparable drugs. There are currently no generic alternatives for Byetta. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Alpha Glucosidase Inhibitors 28
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ACARBOSE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glitazone / Biguanide Combinations 117
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METFORMIN; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
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Bayer Breeze 2 test strips are used to measure glucose in the blood.
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Bayer Breeze 2 test strips are used to measure glucose in the blood.
SGLT2 Inhibitor / Biguanide Combinations 398
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DAPAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Gliptin / Biguanide Combinations 397
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Metformin/saxagliptin (Kombiglyze XR) is an expensive drug used to treat type 2 diabetes. This medicine lowers blood sugar. This drug is less popular than comparable drugs. There are currently no generic alternatives to Kombiglyze XR. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Gliptin / Biguanide Combinations 173
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ALOGLIPTIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Test Strips N/A N/A See Prices
Sulfonylureas 9
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GLYBURIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
SGLT2 Inhibitor / Biguanide Combinations 436
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EMPAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
SGLT2 Inhibitor / Biguanide Combinations 439
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CANAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Insulins 506
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Humalog 50/50 (insulin lispro) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Biguanides 2,892
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Metformin ER (Fortamet) is an expensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Test Strips N/A N/A See Prices
TRUEtest Strips are compatible with the TRUEresult Meter and the TRUE2go Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
Biguanides 403
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Metformin (Riomet) is an expensive drug used to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug is less popular than comparable drugs. There are currently no generic options for Riomet. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Gliptin / Glitazone Combinations 387
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ALOGLIPTIN; PIOGLITAZONE is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with diet and exercise.
Gliptin / Biguanide Combinations 386
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LINAGLIPTIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Ergot Derivatives 453
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BROMOCRIPTINE is used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 650
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Soliqua 100/33 (insulin glargine and lixisenatide) is an expensive drug used to treat diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Glitazone / Biguanide Combinations 654
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METFORMIN; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Alpha Glucosidase Inhibitors 219
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MIGLITOL helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Amlyn Analogues 837
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PRAMLINTIDE is a man-made form of a hormone normally found in the body. It is used to treat type 1 and type 2 diabetes in adults. This medicine works with insulin to control blood sugar.
Insulins 318
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Afrezza (insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Sulfonylureas 84
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TOLAZAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Glitazone / Sulfonylurea Combinations 212
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GLIMEPIRIDE; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
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Glitazones 172
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ROSIGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glinide / Biguanide Combinations 24
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METFORMIN; REPAGLINIDE is used to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body to use insulin better.
Sulfonylureas 53
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CHLORPROPAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Sulfonylureas 81
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TOLBUTAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Insulins N/A N/A See Prices
Insulins N/A N/A See Prices
INSULIN DEGLUDEC; LIRAGLUTIDE is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
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TRUEbalance Test Strips are compatible with the TRUEbalance Meter, and are sold in packages of 50 or 100.
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Prodigy AutoCode (No Coding) Test Strips are compatible with all Prodigy meters (Prodigy AutoCode Meter, Prodigy Pocket Meter, Prodigy Voice Meter) and are sold in packages of 50.
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Sulfonylureas 111
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Test Strips N/A N/A See Prices
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TRUEread Test Strips are compatible with the TRUEread Meter, and are sold in packages of 50 or 100.
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Prodigy AutoCode (No Coding) Test Strips are compatible with all Prodigy meters (Prodigy AutoCode Meter, Prodigy Pocket Meter, Prodigy Voice Meter) and are sold in packages of 50.
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TRUEbalance Test Strips are compatible with the TRUEbalance Meter, and are sold in packages of 50 or 100.
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GLP-1 Agonists 571
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LIXISENATIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
SGLT2 Inhibitor / Biguanide Combinations N/A N/A See Prices
EMPAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Glitazone / Biguanide Combinations 150
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METFORMIN; ROSIGLITAZONE is a combination medicine used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glitazone / Sulfonylurea Combinations 249
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Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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