Diabetes Type 2 Medication

Popular Diabetes Type 2 Drugs

Popularity Drug Name Drug Class Price Price Trend
Biguanides 5
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Metformin (Glucophage) is an inexpensive drug used to treat high blood sugar levels caused by type 2 diabetes. It is is more popular than comparable drugs. It is available in both brand and generic versions. Generic metformin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Insulins 381
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Lantus (insulin glargine) is an expensive, long-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. It is more popular than comparable drugs. There are currently no generic alternatives for any insulin brand. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Biguanides 9
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Metformin ER (Glucophage XR) is an inexpensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly more popular than comparable drugs. It is available in brand and generic versions. Generic metformin ER is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Sulfonylureas 8
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GLIPIZIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
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Sulfonylureas 14
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GLIMEPIRIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body use insulin better.
Insulins 501
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Humalog (insulin lispro) is an expensive, short-acting type of insulin. Insulin helps to control blood sugar levels in diabetes mellitus, including diabetes type 1 and diabetes type 2. It is slightly more popular than comparable drugs. There are currently no generic alternatives for any insulin brand. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Test Strips N/A N/A See Prices
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Sulfonylureas 13
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GLIPIZIDE helps to treat type 2 diabetes. It is combined with diet and exercise. The medicine helps your body to use insulin better.
Insulins 501
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Novolog (insulin aspart) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly more popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptins 372
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Sitagliptin (Januvia) is an expensive drug used to treat type 2 diabetes. It helps to control blood sugar. This drug is more popular than comparable drugs. A generic version of Januvia may become available in 2022. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Medical Supplies and Devices 155 N/A See Prices
Test Strips 155 N/A See Prices
Glitazones 11
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PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Sulfonylureas 15
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GLYBURIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
SGLT2 Inhibitors 400
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Canagliflozin (Invokana) is an expensive drug used to treat type 2 diabetes. It helps to control blood sugar. This drug is more popular than comparable drugs. There are currently no generic alternatives to Invokana. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 757
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Liraglutide (Victoza) is an expensive drug used to improve blood sugar control in adults with type 2 diabetes. This drug is more popular than comparable drugs. There are currently no generic alternatives to Victoza. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Test Strips N/A N/A See Prices
Insulins 412
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Levemir (insulin detemir) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptins 365
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Linagliptin helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Gliptin / Biguanide Combinations 372
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Metformin/sitagliptin (Janumet) is an expensive drug used to treat type 2 diabetes. This medicine lowers blood sugar. This drug is more popular than comparable drugs. A generic form of Janumet may become available in 2027. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Insulins 446
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Humulin N (insulin human) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Insulins 344
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Toujeo (insulin glargine) is an expensive drug used to lower the amount of sugar in your blood. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 635
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DULAGLUTIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
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Bayer Contour test strips are used to measure glucose in the blood.
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Bayer Contour test strips are used to measure glucose in the blood.
Insulins 146
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Humulin R (insulin human) is an expensive drug used to control blood sugar levels in diabetes mellitus including diabetes type 1 and diabetes type 2. This drug is slightly less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
SGLT2 Inhibitors 400
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EMPAGLIGLOZIN helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 446
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Humulin 70/30 (insulin human) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Biguanides 472
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Metformin ER (Fortamet) is an expensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Insulins 501
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Novolog 70/30 (insulin aspart) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptin / Biguanide Combinations 372
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METFORMIN; SITAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Sulfonylurea / Biguanide Combinations 11
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GLYBURIDE; METFORMIN to treat type 2 diabetes. It is combined with a diet and exercise. This medicine helps your body to use insulin better.
SGLT2 Inhibitors 400
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DAPAGLIFLOZIN helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 146
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Novolin 70/30 (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
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Bile Acid Sequestrants 574
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Colesevelam (Welchol) is an expensive drug used to lower in patients who are at risk of heart disease. This drug is more popular than comparable drugs. There are currently no generic alternatives to Welchol. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 585
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EXENATIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
Insulins 501
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Humalog 75/25 (insulin lispro) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Insulins 146
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Novolin N (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Sulfonylurea / Biguanide Combinations 30
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GLIPIZIDE; METFORMIN helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body to use insulin better.
Medical Supplies and Devices N/A N/A See Prices
Medical Supplies and Devices N/A N/A See Prices
Insulins 541
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Tresiba (insulin degludec) is an expensive drug used to lower the amount of sugar in your blood. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Glinides 34
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REPAGLINIDE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Insulins 146
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Novolin R (human insulin) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
SGLT2 Inhibitor / Biguanide Combinations 400
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CANAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
GLP-1 Agonists 487
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ALBIGLUTIDE is used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines.
Insulins 501
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Apidra (insulin glulisine) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Gliptins 173
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ALOGLIPTIN (al oh glip tin) helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
SGLT2 Inhibitor / Gliptin Combinations 517
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EMPAGLIFLOZIN; LINAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Glinides 72
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NATEGLINIDE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Gliptin / Biguanide Combinations 365
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METFORMIN; LINAGLIPTIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Gliptins 372
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SAXAGLIPTIN helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glitazone / Biguanide Combinations 110
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METFORMIN; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
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TRUEtrack Test Strips are compatible with the TRUEtrack Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
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TRUEtrack Test Strips are compatible with the TRUEtrack Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
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Bayer Breeze 2 test strips are used to measure glucose in the blood.
Test Strips N/A N/A See Prices
Bayer Breeze 2 test strips are used to measure glucose in the blood.
Gliptin / Biguanide Combinations 372
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Metformin/saxagliptin (Kombiglyze XR) is an expensive drug used to treat type 2 diabetes. This medicine lowers blood sugar. This drug is less popular than comparable drugs. There are currently no generic alternatives to Kombiglyze XR. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
GLP-1 Agonists 616
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Exenatide (Byetta) is an expensive drug used to improve blood sugar control in adults with type 2 diabetes. This medicine may be used with other oral diabetes medicines. This drug is less popular than comparable drugs. There are currently no generic alternatives for Byetta. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Alpha Glucosidase Inhibitors 31
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ACARBOSE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
SGLT2 Inhibitor / Biguanide Combinations 400
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DAPAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Test Strips N/A N/A See Prices
TRUEtest Strips are compatible with the TRUEresult Meter and the TRUE2go Meter, and are sold in packages of 50 or 100. They are also sold under many retail store brands and may be compatible with store brand meters.
Biguanides 5,056
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Metformin ER (Fortamet) is an expensive drug used to treat type II diabetes. It helps control blood sugar in combination with diet and exercise. This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Test Strips N/A N/A See Prices
Medical Supplies and Devices N/A N/A See Prices
Gliptin / Biguanide Combinations 173
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ALOGLIPTIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Sulfonylureas 10
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GLYBURIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. The medicine helps your body to use insulin better.
Insulins 501
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Humalog 50/50 (insulin lispro) is an expensive drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Medical Supplies and Devices N/A N/A See Prices
Test Strips N/A N/A See Prices
SGLT2 Inhibitor / Biguanide Combinations 400
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EMPAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Biguanides 399
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Metformin (Riomet) is an expensive drug used to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug is less popular than comparable drugs. There are currently no generic options for Riomet. It is covered by some Medicare and insurance plans, but pharmacy coupons or cash prices may be lower.
Gliptin / Glitazone Combinations 372
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ALOGLIPTIN; PIOGLITAZONE is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with diet and exercise.
Glitazone / Biguanide Combinations 630
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METFORMIN; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Ergot Derivatives 416
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BROMOCRIPTINE is used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Alpha Glucosidase Inhibitors 197
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MIGLITOL helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Amlyn Analogues 754
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PRAMLINTIDE is a man-made form of a hormone normally found in the body. It is used to treat type 1 and type 2 diabetes in adults. This medicine works with insulin to control blood sugar.
SGLT2 Inhibitor / Biguanide Combinations 400
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CANAGLIFLOZIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Insulins 234
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Afrezza (insulin) is a moderately priced drug used to treat diabetes mellitus, including diabetes type 1 and diabetes type 2. This drug is less popular than comparable drugs. There are currently no generic options for any insulin brand, but less expensive biosimilar versions may be available in the future. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Glitazone / Sulfonylurea Combinations 349
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GLIMEPIRIDE; PIOGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Gliptin / Biguanide Combinations 365
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LINAGLIPTIN; METFORMIN is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.
Medical Supplies and Devices N/A N/A See Prices
Test Strips N/A N/A See Prices
Sulfonylureas 54
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CHLORPROPAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Sulfonylureas 90
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TOLAZAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Glitazones 156
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ROSIGLITAZONE helps to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glinide / Biguanide Combinations 394
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METFORMIN; REPAGLINIDE is used to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body to use insulin better.
Insulins N/A N/A See Prices
Insulins N/A N/A See Prices
Insulins N/A N/A See Prices
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TRUEbalance Test Strips are compatible with the TRUEbalance Meter, and are sold in packages of 50 or 100.
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Prodigy AutoCode (No Coding) Test Strips are compatible with all Prodigy meters (Prodigy AutoCode Meter, Prodigy Pocket Meter, Prodigy Voice Meter) and are sold in packages of 50.
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Sulfonylureas 81
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TOLBUTAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better.
Sulfonylureas 107
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Test Strips N/A N/A See Prices
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TRUEread Test Strips are compatible with the TRUEread Meter, and are sold in packages of 50 or 100.
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Prodigy AutoCode (No Coding) Test Strips are compatible with all Prodigy meters (Prodigy AutoCode Meter, Prodigy Pocket Meter, Prodigy Voice Meter) and are sold in packages of 50.
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TRUEbalance Test Strips are compatible with the TRUEbalance Meter, and are sold in packages of 50 or 100.
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GLP-1 Agonists N/A N/A See Prices
Glitazone / Biguanide Combinations 146
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METFORMIN; ROSIGLITAZONE is a combination medicine used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise.
Glitazone / Sulfonylurea Combinations 253
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Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.