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Gliptin / Biguanide Combinations

Gliptin / biguanide combinations are used to treat diabetes type 2. Gliptins lower blood sugar levels by increasing insulin and suppressing glucagon. Biguanides does so by decreasing the amount of glucose absorbed through the intestines and made by the liver, and making the body more sensitive to insulin.

Why are gliptin biguanide combinations prescribed?

  1. Diabetes Type 2 (100%)

Key takeaways

Gliptin / biguanide combinations are used to treat Type 2 diabetes. They work by combining two types of diabetes treatments: gliptins, which increase insulin production and decrease glucose (sugar) production in the liver, and biguanides, which improve the body's response to insulin and reduce glucose absorption in the intestines. These medications are available as oral tabletd. Examples include sitagliptin / metformin (Janumet, Janumet XR), alogliptin / metformin (Kazano), and saxagliptin / metformin (Kombiglyze XR). You can discuss with your healthcare team which option might be right for you.

Prices for popular Gliptin / Biguanide Combinations medications
Viewing 8 of 8 medications
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Janumet

as low as$322
Janumet (metformin/sitagliptin) is used to treat type 2 diabetes. Janumet is a gliptin biguanide combination which works by lowering blood sugar levels. The most common form of Janumet is a 50mg/1000mg tablet. It is also avalible as a 50mg/500mg tablet. There are currently no generic alterantives for Janumet. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Kazano (alogliptin / metformin)

as low as$165
ALOGLIPTIN; METFORMIN treats type 2 diabetes. It works by decreasing your blood sugar (glucose). Changes to diet and exercise are often combined with this medication.
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Janumet XR

as low as$322
SITAGLIPTIN; METFORMIN treats type 2 diabetes. It works by decreasing your blood sugar (glucose). Changes to diet and exercise are often combined with this medication.
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Kombiglyze XR (saxagliptin / metformin ER)

as low as$72
Kombiglyze XR is used to lower blood sugar and treat type 2 diabetes. Kombiglyze XR is less popular than other gliptin/biguanide combinations. There are currently no generic alternatives to Kombiglyze XR.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Kombiglyze XR is not covered by most Medicare and insurance plans.
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Zituvimet (sitagliptin / metformin)

as low as$246
Zituvimet is part of the Gliptin / Biguanide Combinations class and treats Diabetes Type 2. Gliptin / biguanide combinations are used to treat diabetes type 2. Gliptins lower blood sugar levels by increasing insulin and suppressing glucagon. Biguanides does so by decreasing the amount of glucose absorbed through the intestines and made by the liver, and making the body more sensitive to insulin. Zituvimet is only available as a brand name drug.
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Zituvimet XR

as low as$322
Zituvimet XR is part of the Gliptin / Biguanide Combinations class and treats Diabetes Type 2. Gliptin / biguanide combinations are used to treat diabetes type 2. Gliptins lower blood sugar levels by increasing insulin and suppressing glucagon. Biguanides does so by decreasing the amount of glucose absorbed through the intestines and made by the liver, and making the body more sensitive to insulin. Zituvimet XR is only available as a brand name drug.
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Jentadueto

as low as$344
Jentadueto (metformin and linagliptin) is used to lower blood sugar and treat type 2 diabetes. Jentadueto is slightly more popular than other gliptin/biguanide combinations. There are currently no generic alternatives to Jentadueto.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Jentadueto is covered by some Medicare and insurance plans.
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Jentadueto XR

as low as$344
Jentadueto XR (metformin and linagliptin) is used to lower blood sugar and treat type 2 diabetes. Jentadueto XR is slightly more popular than other gliptin/biguanide combinations. There are currently no generic alternatives to Jentadueto XR

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Jentadueto XR is covered by most Medicare and insurance plans.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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