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Compare Janumet vs. Janumet XR

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Janumet (sitagliptin / metformin)
    Janumet xr (sitagliptin / metformin)
  • Janumet (sitagliptin / metformin)
    Janumet xr (sitagliptin / metformin)

  • Summary of Janumet vs. Janumet XR

    Summary for DPP-4 inhibitor / Biguanide
    Prescription only

    Janumet (sitagliptin / metformin) is a medication for adults with Type 2 diabetes. It contains two different diabetes medications that work together to help control blood sugar. One is sitagliptin, a DPP-4 inhibitor, and the other is metformin, a biguanide. The Janumet immediate-release tablets are taken by mouth twice a day. It works best when used with a balanced meal plan and exercise routine. Some side effects are diarrhea, upper respiratory tract infection, and headache. There's only a brand-name version of Janumet; there's no generic version yet.

    Summary for DPP-4 inhibitor / Biguanide
    Prescription only

    Janumet XR (sitagliptin / metformin) is a combination medication for adults with Type 2 diabetes. It contains two different diabetes medications that help improve blood sugar control. One is sitagliptin, a DPP-4 inhibitor, and the other is metformin, a biguanide. Janumet XR is an extended-release tablet that you take once a day. To get the most out of the medication, take it along with a balanced diet and regular exercise. Some side effects are diarrhea, upper respiratory tract infection, and headache. Currently, this medication is brand name only; there's no generic version available.

  • Indications of Janumet vs. Janumet XR

    Indications for
    •Type 2 diabetes
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Janumet vs. Janumet XR

    Pros and Const for DPP-4 inhibitor / Biguanide
    Pros
    •Combines the effects of two diabetes medications into one tablet
    •Less likely to cause weight gain and low blood sugar compared to other diabetes medications
    •Can lower A1C by up to 2% in 6 months
    Cons
    •Must take twice a day with meals
    •Only available as a fixed dose, so can be hard to make dose adjustments
    •Not a good option for people with severe kidney problems
    •Not approved for people with Type 1 diabetes
    Pros and Const for DPP-4 inhibitor / Biguanide
    Pros
    •Only need to take once a day
    •Combines the effects of two diabetes medications into one tablet
    •Less likely to cause weight gain and low blood sugar compared to other diabetes medications
    Cons
    •Only available as a fixed dose, so can be hard to make dose adjustments
    •Not a good option for people with severe kidney problems
    •Not approved for people with Type 1 diabetes

  • Common Side Effects of Janumet vs. Janumet XR

    Common Side Effects for
    •Diarrhea (8%)
    •Upper respiratory tract infection (6%)
    •Headache (6%)
    Common Side Effects for
    •Diarrhea (8%)
    •Upper respiratory tract infection (6%)
    •Headache (6%)

  • Warnings of Janumet vs. Janumet XR

    Common Side Effects for
    •Lactic acidosis
    •Inflammation of the pancreas (pancreatitis)
    •Risk of heart failure
    •Sudden kidney problems
    •Low vitamin B12 levels
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Joint pain
    •Severe skin reaction
    •Serious allergic reactions
    Common Side Effects for
    •Lactic acidosis
    •Inflammation of the pancreas (pancreatitis)
    •Risk of heart failure
    •Sudden kidney problems
    •Low vitamin B12 levels
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Joint pain
    •Severe skin reaction
    •Serious allergic reactions

  • Prices with our coupons for Janumet vs. Janumet XR

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    Learn more about Janumet xr

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