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Compare Farxiga vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Farxiga (dapagliflozin) and Glucotrol (glipizide) are medications used to treat Type 2 diabetes, but they some differences between them. Farxiga helps lower blood sugar by causing your body to get rid of excess sugar through your urine. It also has benefits for heart failure and chronic kidney disease (CKD). On the other hand, Glucotrol works to lower blood sugar by telling your pancreas to release more insulin. Farxiga is taken once daily and only available as a brand medication, while Glucotrol can be taken once or twice daily and is available as a lower-cost generic. Farxiga has a lower risk of causing low blood sugar but can increase the risk of urinary tract infections and dehydration. In contrast, Glucotrol has a higher risk of causing low blood sugar (hypoglycemia) and can lead to weight gain.

  • Farxiga (dapagliflozin)
    Glipizide
  • Farxiga (dapagliflozin)
    Glipizide

  • Summary of Farxiga vs. Glucotrol

    Summary for SGLT2 inhibitor
    Prescription only

    Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

    Summary for Sulfonylurea
    Prescription only

    Glipizide is a sulfonylurea medication used to treat Type 2 diabetes in adults. It lowers blood sugar levels by telling your pancreas to release more insulin. Glipizide is taken by mouth, typically once or twice daily. Some side effects of this medication include dizziness and diarrhea. Taking glipizide can also put you at risk for dangerously low blood sugar, so it's important to take this medication with meals.

  • Indications of Farxiga vs. Glucotrol

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
    •Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in people with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Farxiga vs. Glucotrol

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken only once daily
    •Low risk of causing low blood sugar when taken by itself
    •Can take with other diabetes medications
    Cons
    •Raises risk of yeast infections and urinary tract infections (UTIs)
    •Not available as a liquid
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for Sulfonylurea
    Pros
    •Taken by mouth
    •Extended-release tablets taken once daily
    •Available as a lower-cost generic medication
    Cons
    •Raises your risk for low blood sugar levels (hypoglycemia)
    •Need to take with meals or 30 minutes before a meal
    •Can cause some weight gain as a side effect

  • Common Side Effects of Farxiga vs. Glucotrol

    Common Side Effects for
    •Vaginal yeast infection in females (7-8%)
    •Nose and throat infection (6-7%)
    •Urinary tract infection (UTI, 4-6%)
    Common Side Effects for
    •Dizziness (7%)
    •Diarrhea (5%)
    •Nervousness (4%)
    •Tremor (4%)
    •Passing gas (3%)
    •Low blood sugar levels (3%)

    Note: Side effects were reported by people who took glipizide ER (Glucotrol XL) in clinical studies.

  • Warnings of Farxiga vs. Glucotrol

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    Common Side Effects for
    •Low blood sugar levels
    •Risk of low red blood cell count (hemolytic anemia)
    •Possible risk of serious heart problems
    •Risk of harm in people with certain stomach problems (extended-release tablets)

  • Prices with our coupons for Farxiga vs. Glucotrol

    Learn more about Farxiga
    Learn more about Glipizide

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