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Compare Farxiga vs. Ozempic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dapagliflozin (Farxiga) and semaglutide (Ozempic) are both medications used to treat Type 2 diabetes and help lower the risk of heart problems in adults with heart disease. However, they belong to different medication classes and have distinct characteristics. Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor taken orally once a day, while semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist given as a subcutaneous (under the skin) injection once a week. Dapagliflozin is available in both brand-name and generic forms, whereas semaglutide is only available as a brand-name medication. Common side effects of dapagliflozin include urinary tract infections, yeast infections, and increased urination, while semaglutide can cause nausea, vomiting, and diarrhea. Dapagliflozin and semaglutide both have an increased risk of low blood sugar when combined with other diabetes medications.

Farxiga (dapagliflozin)
Ozempic (semaglutide)
Farxiga (dapagliflozin)
Ozempic (semaglutide)
Summary of Farxiga vs. Ozempic
Summary for SGLT2 inhibitor
Prescription only
Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.
Summary for GLP-1 agonist
Prescription only
Ozempic (semaglutide) is a GLP-1 agonist used with diet and exercise to help adults manage Type 2 diabetes. It can also lower the risk of heart attack, stroke, and heart-related death in some people with Type 2 diabetes. It comes as a once-weekly injection under the skin and as a tablet taken by mouth once a day. The injection is also approved to help slow worsening kidney problems in people with Type 2 diabetes and chronic kidney disease (CKD). Common side effects include nausea, vomiting, and diarrhea.
Indications of Farxiga vs. Ozempic
Indications for

•Type 2 diabetes (in addition to diet and exercise) in people age 10 and over

•Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease

•Lowering the risk of hospitalization and death due to heart problems in people with heart failure

•Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)

Indications for
Injection:

•Type 2 diabetes

•Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes and heart disease

•Lower the risk of worsening kidney problems and heart-related death in adults with Type 2 diabetes and chronic kidney disease (CKD)

Tablets:

•Type 2 diabetes

•Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes at high risk for these events
Pros and Cons of Farxiga vs. Ozempic
Pros and Const for SGLT2 inhibitor
Pros

•Taken only once daily

•Low risk of causing low blood sugar when taken by itself

•Can take with other diabetes medications

Cons

•Raises risk of yeast infections and urinary tract infections (UTIs)

•Not available as a liquid

•Not recommended during the second and third trimesters of pregnancy

Pros and Const for GLP-1 agonist
Pros

•Only given once per week

•Might help you lose weight

•Helps lower the risk of heart problems and kidney problems in people with type 2 diabetes

•Available as an injection and an oral tablet

Cons

•Commonly causes nausea, vomiting, and diarrhea

•Risk of low blood sugar if taken with certain diabetes medications

•Can't be used for Type 1 diabetes

•Interacts with medications taken by mouth
Common Side Effects of Farxiga vs. Ozempic
Common Side Effects for

•Vaginal yeast infection in females (7-8%)

•Nose and throat infection (6-7%)

•Urinary tract infection (UTI, 4-6%)

Common Side Effects for

•Nausea (16-20%)

•Diarrhea (9%)

•Vomiting (5-9%)

•Stomach pain (6-7%)

•Constipation (3-5%)

Note: Side effects listed above are for Ozempic (semaglutide) injection
Warnings of Farxiga vs. Ozempic
Common Side Effects for

•Ketoacidosis

•Low fluids in the body (leading to low blood pressure or dehydration)

•Genital and urinary tract infections

•Low blood sugar (hypoglycemia) when used with other diabetes medications

Common Side Effects for

•Risk of thyroid tumors

•Inflammation of the pancreas (pancreatitis)

•Eye problems

•Low blood sugar (hypoglycemia) when taken with certain diabetes medications

•Kidney damage

•Severe stomach problems

•Severe allergic reactions

•Gallbladder problems

•Lung problems during anesthesia or deep sedation
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Compare Farxiga vs. Ozempic

Key takeaways

Summary of Farxiga vs. Ozempic

Indications of Farxiga vs. Ozempic

Pros and Cons of Farxiga vs. Ozempic

Common Side Effects of Farxiga vs. Ozempic

Warnings of Farxiga vs. Ozempic

Prices with our coupons for Farxiga vs. Ozempic

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