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Compare Farxiga vs. Ozempic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dapagliflozin (Farxiga) and semaglutide (Ozempic) are both medications used to treat Type 2 diabetes and help lower the risk of heart problems in adults with heart disease. However, they belong to different medication classes and have distinct characteristics. Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor taken orally once a day, while semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist given as a subcutaneous (under the skin) injection once a week. Dapagliflozin is available in both brand-name and generic forms, whereas semaglutide is only available as a brand-name medication. Common side effects of dapagliflozin include urinary tract infections, yeast infections, and increased urination, while semaglutide can cause nausea, vomiting, and diarrhea. Dapagliflozin and semaglutide both have an increased risk of low blood sugar when combined with other diabetes medications.

  • Farxiga (dapagliflozin)
    Ozempic (semaglutide)
  • Farxiga (dapagliflozin)
    Ozempic (semaglutide)

  • Summary of Farxiga vs. Ozempic

    Summary for SGLT2 inhibitor
    Prescription only

    Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

    Summary for GLP-1 agonist
    Prescription only

    Ozempic (semaglutide) is a prescription injection used with diet and exercise to help manage Type 2 diabetes in adults. It's also FDA approved to lower the risk of heart attack, stroke, and heart-related death in those with Type 2 diabetes and heart disease. In addition, it can reduce the risk of worsening kidney problems in people with Type 2 diabetes and chronic kidney disease (CKD). Ozempic (semaglutide) is a GLP-1 agonist that's injected under the skin once a week. Common side effects include nausea, vomiting, and diarrhea.

  • Indications of Farxiga vs. Ozempic

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
    •Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in people with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for
    •Type 2 diabetes
    •Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes and heart disease
    •Lower the risk of worsening kidney problems and heart-related death in adults with Type 2 diabetes and chronic kidney disease (CKD)

  • Pros and Cons of Farxiga vs. Ozempic

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken only once daily
    •Low risk of causing low blood sugar when taken by itself
    •Can take with other diabetes medications
    Cons
    •Raises risk of yeast infections and urinary tract infections (UTIs)
    •Not available as a liquid
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for GLP-1 agonist
    Pros
    •Only given once per week
    •Might help you lose weight
    •Helps lower the risk of heart problems and kidney problems in people with type 2 diabetes
    •Can store open and used pens at room temperature for up to 8 weeks
    Cons
    •Is an injection given under the skin
    •Commonly causes nausea, vomiting, and diarrhea
    •Risk of low blood sugar if taken with certain diabetes medications
    •Can't be used for Type 1 diabetes

  • Common Side Effects of Farxiga vs. Ozempic

    Common Side Effects for
    •Vaginal yeast infection in females (7-8%)
    •Nose and throat infection (6-7%)
    •Urinary tract infection (UTI, 4-6%)
    Common Side Effects for
    •Nausea (16-20%)
    •Diarrhea (9%)
    •Vomiting (5-9%)
    •Stomach pain (6-7%)
    •Constipation (3-5%)

  • Warnings of Farxiga vs. Ozempic

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    Common Side Effects for
    •Risk of thyroid tumors
    •Inflammation of the pancreas (pancreatitis)
    •Eye problems
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Kidney damage
    •Severe stomach problems
    •Severe allergic reactions
    •Gallbladder problems
    •Lung problems during anesthesia or deep sedation

  • Prices with our coupons for Farxiga vs. Ozempic

    Learn more about Farxiga
    Learn more about Ozempic

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