Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Farxiga vs. Glyburide

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Farxiga (dapagliflozin) and Glyburide (Glynase) are both medications used to manage Type 2 diabetes. Both help lower your blood sugar (glucose), but they have several differences between them. Farxiga works by causing your kidneys to remove excess sugar through urine. It also has benefits for people with heart failure and chronic kidney disease (CKD). Glyburide, on the other hand, sends signals to your pancreas to release more insulin. Farxiga is typically taken once daily and is only available as a brand medication, while Glyburide can be taken once or twice daily and is available in both generic and brand forms. Farxiga has a lower risk of causing low blood sugar compared to Glyburide. Additionally, Farxiga isn't recommended during the second and third trimesters of pregnancy, whereas Glyburide's safety during pregnancy is not well-studied.

  • Farxiga (dapagliflozin)
    Glyburide
  • Farxiga (dapagliflozin)
    Glyburide

  • Summary of Farxiga vs. Glyburide

    Summary for SGLT2 inhibitor
    Prescription only

    Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

    Summary for Sulfonylurea
    Prescription only

    Glyburide is taken by mouth to lower blood sugar levels for people who have Type 2 diabetes. This medication isn't meant to be taken alone, but in addition to eating a healthy diet and engaging in regular exercise. Glyburide is typically taken once or twice daily, depending on your dose.

  • Indications of Farxiga vs. Glyburide

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
    •Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in people with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for
    •Type 2 diabetes

  • Pros and Cons of Farxiga vs. Glyburide

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken only once daily
    •Low risk of causing low blood sugar when taken by itself
    •Can take with other diabetes medications
    Cons
    •Raises risk of yeast infections and urinary tract infections (UTIs)
    •Not available as a liquid
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for Sulfonylurea
    Pros
    •Usually taken only once daily with largest meal
    •Can lower A1C levels by 1.5%
    •Taken by mouth, so good option for people who don't like injections
    •Can be taken with some other blood sugar medications, such as metformin
    Cons
    •Risk of low blood sugar (hypoglycemia), especially if you have kidney or liver problems
    •More likely to cause low blood sugar than other blood sugar medications, such as metformin
    •Can cause some weight gain
    •Not approved for Type 1 diabetes

  • Common Side Effects of Farxiga vs. Glyburide

    Common Side Effects for
    •Vaginal yeast infection in females (7-8%)
    •Nose and throat infection (6-7%)
    •Urinary tract infection (UTI, 4-6%)
    Common Side Effects for
    •Feeling bloated
    •Nausea
    •Heartburn

  • Warnings of Farxiga vs. Glyburide

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    Common Side Effects for
    •Low blood sugar (hypoglycemia)
    •Possible risk of heart problems
    •Breakdown of red blood cells

  • Prices with our coupons for Farxiga vs. Glyburide

    Learn more about Farxiga
    Learn more about Glyburide

Compare other Diabetes Type 2 drugs

Brenzavvy vs FarxigaEntresto vs FarxigaFarxiga vs ActosFarxiga vs AfrezzaFarxiga vs GlucotrolFarxiga vs GlyburideFarxiga vs InvokanaFarxiga vs JardianceFarxiga vs KerendiaFarxiga vs MetforminFarxiga vs OzempicFarxiga vs RybelsusFarxiga vs WegovyInpefa vs FarxigaJanuvia vs FarxigaSteglatro vs FarxigaActos vs BaqsimiActos vs InvokanaBrenzavvy vs JardianceEntresto vs JardianceEntresto vs LisinoprilEntresto vs LosartanEntresto vs RanexaEntresto vs ValsartanGlucotrol vs ActosGlyburide vs ActosHumalog vs ActosHuman Insulin vs ActosVasotec vs EntrestoVerquvo vs Entresto
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.