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Compare Farxiga vs. Kerendia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dapagliflozin (Farxiga) and finerenone (Kerendia) are both oral medications used to help protect your kidneys if you have chronic kidney disease (CKD) caused by Type 2 diabetes. However, they belong to different medication classes and work in different ways. Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that helps remove extra sugar and sodium through urine, while finerenone is a mineralocorticoid receptor antagonist that blocks hormones which cause inflammation and scarring. Dapagliflozin is also used to lower blood sugar in Type 2 diabetes and reduce heart failure risks, whereas finerenone is specifically for people who have CKD and Type 2 diabetes. Dapagliflozin is available in both brand and generic forms, while finerenone is only available as a brand name medication. Common side effects of dapagliflozin include urinary tract infections, yeast infections, and increased urination, while finerenone can cause high potassium levels and low blood pressure. Dapagliflozin may interact with other diabetes medications and diuretics, whereas finerenone can interact with medications that raise potassium levels.

  • Farxiga (dapagliflozin)
    Kerendia (finerenone)
  • Farxiga (dapagliflozin)
    Kerendia (finerenone)

  • Summary of Farxiga vs. Kerendia

    Summary for SGLT2 inhibitor
    Prescription only

    Farxiga, the brand name for dapagliflozin, is used together with a nutritious diet and exercise plan to lower blood sugar levels in people 10 years and older with Type 2 diabetes. It can also help lower the risk of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Farxiga (dapagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's taken by mouth once a day. Some side effects include yeast infections, urinating more often, and weight loss.

    Summary for Mineralocorticoid receptor antagonist
    Prescription only

    Kerendia (finerenone) is a mineralocorticoid receptor antagonist that helps protect your kidneys and heart if you have chronic kidney disease (CKD) caused by Type 2 diabetes. It's FDA approved to slow kidney damage, lower the risk of kidney failure, and reduce the chances of heart-related problems like heart attacks and heart failure hospitalizations. Kerendia (finerenone) comes as a tablet that you take once a day by mouth. Your dose depends on your kidney function and how you respond to the medication. Common side effects include high potassium levels, low blood pressure, and low sodium levels.

  • Indications of Farxiga vs. Kerendia

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 and over
    •Lowering the risk of hospitalization for heart failure in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in people with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization for heart failure, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for

    Lowers the risk of serious health problems in adults with chronic kidney disease (CKD) caused by Type 2 diabetes, including:

    •Worsening kidney function
    •Death from heart problems
    •Heart attacks
    •Hospitalization due to heart failure

  • Pros and Cons of Farxiga vs. Kerendia

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken only once daily
    •Low risk of causing low blood sugar when taken by itself
    •Can take with other diabetes medications
    Cons
    •Raises risk of yeast infections and urinary tract infections (UTIs)
    •Not available as a liquid
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for Mineralocorticoid receptor antagonist
    Pros
    •Protects your kidneys and lowers heart risks
    •Taken by mouth once per day
    •Can be taken with or without food
    Cons
    •Won't be able to "feel" the medication working
    •Can raise blood potassium levels
    •Requires regular blood test to check potassium levels and kidney function

  • Common Side Effects of Farxiga vs. Kerendia

    Common Side Effects for
    •Vaginal yeast infection in females (7-8%)
    •Nose and throat infection (6-7%)
    •Urinary tract infection (UTI, 4-6%)
    Common Side Effects for
    •High blood potassium levels (14%)

  • Warnings of Farxiga vs. Kerendia

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    Common Side Effects for
    •High potassium levels

  • Prices with our coupons for Farxiga vs. Kerendia

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