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Mineralocorticoid Receptor Antagonists

Mineralocorticoid receptor antagonists are used to treat heart failure, hypertension, hyperaldosteronism, hypokalemia and edema caused by kidney disease and cirrhosis. They work by getting rid of excess salt and water from the kidney.

Why are mineralocorticoid receptor antagonists prescribed?

  1. Heart Failure (21%)
  2. Hypertension (21%)
  3. Edema (20%)
  4. Aldosteronism (20%)
  5. Cirrhosis (20%)
  6. Kidney Disease (0%)
  7. Hypokalemia (0%)

Key takeaways

Mineralocorticoid receptor antagonists block the action of aldosterone, a hormone that causes your body to retain sodium and water. This action helps the body get rid of excess salt and water. Mineralocorticoid receptor antagonists are used to treat heart failure, high blood pressure, and high aldosterone levels. They can also help with fluid retention caused by certain kidney or liver problems. Examples include spironolactone (Aldactone), eplerenone (Inspra), and finerenone (Kerendia).

Prices for popular Mineralocorticoid Receptor Antagonists medications
Viewing 4 of 4 medications
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Aldactone (spironolactone)

as low as$9
Spironolactone (Aldactone) is a diuretic. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure, and edema or swelling from heart, kidney, or liver disease. It is also used to treat patients who make too much aldosterone or have low potassium. It is more popular than comparable drugs. It is available in generic and brand versions. Generic spironolactone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Inspra (eplerenone)

as low as$59
EPLERENONE treats high blood pressure and heart failure. It may also be used to prevent further damage after a heart attack. It helps your kidneys remove more fluid and salt from your blood through the urine without losing too much potassium. It belongs to a group of medications called diuretics.
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Carospir

as low as$420
SPIRONOLACTONE treats high blood pressure and heart failure. It may also be used to reduce swelling related to heart, kidney, or liver disease. It helps your kidneys remove more fluid and salt from your blood through the urine without losing too much potassium. It belongs to a group of medications called diuretics.
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Kerendia

as low as$664
FINERENONE lowers the risk of worsening kidney disease in people with type 2 diabetes. It may also lower the risk of heart attack, death, and hospitalization for heart failure in people with type 2 diabetes. It works by blocking the effect of the hormone aldosterone in your body. This decreases inflammation and injury in the kidneys, heart, and blood vessels.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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