Compare Triamterene vs. Inspra

Triamterene (Dyrenium) and eplerenone (Inspra) are both medications that help manage fluid levels in your body, but they work differently and are used for different conditions. Triamterene is a potassium-sparing diuretic that helps reduce swelling (edema) by removing extra salt and fluid from your body. It's usually taken twice a day and is often combined with other medications. On the other hand, eplerenone is an aldosterone receptor antagonist that helps lower blood pressure and improve survival after a heart attack by blocking a hormone that raises blood pressure. Eplerenone is typically taken once a day and can be used alone or with other medications. While both medications can cause high potassium levels, eplerenone is also associated with fewer hormone-related side effects compared to similar medications like spironolactone. Additionally, eplerenone is not recommended for people with severe kidney problems, whereas triamterene can increase the risk of kidney stones and gout.