Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Lisinopril (Zestril) and sotalol (Betapace) are both prescription medications, but they serve different purposes and belong to different drug classes. Lisinopril is an ACE inhibitor used primarily to lower blood pressure, treat heart failure, and reduce the risk of death after a heart attack. It works by relaxing blood vessels. On the other hand, Sotalol is an antiarrhythmic medication used to treat and prevent certain types of heart rhythm problems, like atrial fibrillation. It works by blocking potassium channels and beta receptors in the heart to slow down electrical activity and heart rate. Lisinopril is typically taken once daily, while Sotalol is usually taken twice daily and requires initial monitoring in a hospital. Common side effects of Lisinopril include cough and dizziness, whereas Sotalol can cause tiredness, dizziness, and low heart rate. Both medications are available in generic forms, making them more affordable.
Lisinopril (Zestril)
Sotalol (Betapace)
Lisinopril (Zestril)
Sotalol (Betapace)
Summary of Lisinopril vs. Betapace
Summary for ACE inhibitor
Prescription only
Lisinopril (Zestril) is an angiotensin-converting enzyme (ACE) inhibitor that's a first-choice medication used for lowering blood pressure. It's also approved to treat symptoms of heart failure and also to lower the risk of death after a heart attack. Lisinopril (Zestril) is a tablet that's taken by mouth, typically once daily. It's also available as an oral solution. Some common side effects of this medication include cough, dizziness, and headache.
Summary for Antiarrhythmic
Prescription only
Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.