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Compare Bisoprolol vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bisoprolol (bisoprolol fumarate) and lisinopril (Zestril) are both medications used to treat high blood pressure, but they have some distinct differences. Bisoprolol is a beta blocker that works by slowing down the heart rate, allowing the heart to relax between beats. It's typically used when first-choice blood pressure medications are not effective. Common side effects include headache, fatigue, and dizziness. Lisinopril, on the other hand, is an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels by blocking a protein that tightens them. It's a first-choice medication for high blood pressure and is also used to treat heart failure and reduce the risk of death after a heart attack. Lisinopril can cause a dry cough, dizziness, and headache. Unlike bisoprolol, lisinopril should not be used during pregnancy due to the risk of severe harm to the unborn baby. Both medications are available in generic forms, making them more affordable options.

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  • Bisoprolol
    Lisinopril (Zestril)
  • Bisoprolol
    Lisinopril (Zestril)

  • Summary of Bisoprolol vs. Lisinopril

    Summary for Beta blocker
    Prescription only

    Bisoprolol, or bisoprolol fumarate, is a tablet that's used to treat high blood pressure. It belongs to a group of medications called beta blockers. It's usually only given when first-choice blood pressure medications aren't working well enough. Some common side effects of bisoprolol include headache, feeling tired, and diarrhea. It has some interactions with alcohol and taking bisoprolol with alcohol can worsen dizziness and raise the risk for fainting.

    Summary for ACE inhibitor
    Prescription only

    Lisinopril (Zestril) is an angiotensin-converting enzyme (ACE) inhibitor that's a first-choice medication used for lowering blood pressure. It's also approved to treat symptoms of heart failure and also to lower the risk of death after a heart attack. Lisinopril (Zestril) is a tablet that's taken by mouth, typically once daily. It's also available as an oral solution. Some common side effects of this medication include cough, dizziness, and headache.

  • Indications of Bisoprolol vs. Lisinopril

    Indications for
    •High blood pressure
    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk for death after a heart attack

  • Pros and Cons of Bisoprolol vs. Lisinopril

    Pros and Const for Beta blocker
    Pros
    •Works well to lower blood pressure
    •Available as a lower-cost generic
    •Only need to take it once a day
    •Can take it with or without food
    Cons
    •Not a first-choice medication to lower blood pressure
    •Skipping or missing doses can lead to high blood pressure and higher risk of heart attacks
    •Can make you feel more tired
    •Can hide symptoms of low blood sugar if you have diabetes
    Pros and Const for ACE inhibitor
    Pros
    •A first-choice blood pressure medication
    •Taken by mouth once per day
    •Can be taken by children as young as 6 years old for treatment of high blood pressure
    •Available as a liquid (Qbrelis), good option for people who've difficulty swallowing tablets
    Cons
    •More likely to cause a dry cough, compared to ARBs
    •Can't be taken during pregnancy or breastfeeding
    •Might not work as well for lowering high blood pressure in black people

  • Common Side Effects of Bisoprolol vs. Lisinopril

    Common Side Effects for
    •Headache (9%)
    •Fatigue (7%)
    •Upper respiratory tract infection (5%)
    •Swelling in arms or legs (4%)
    •Dizziness (3%)
    •Runny nose (3%)
    Common Side Effects for
    •Dizziness (up to 19%)
    •Low blood pressure (7-11%)
    •Higher creatinine levels (7-10%)
    •Headache (6%)

  • Warnings of Bisoprolol vs. Lisinopril

    Common Side Effects for
    •Heart attack or irregular heart rhythm
    •Heart failure
    •Trouble breathing (people with bronchospastic conditions)
    •Hiding symptoms of low blood sugar
    •Hiding symptoms of high thyroid hormone
    •Severe allergic reactions
    •Worsening of poor circulation
    Common Side Effects for
    •Not for use during pregnancy
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Heart problems due to high potassium
    •Liver problems

  • Prices with our coupons for Bisoprolol vs. Lisinopril

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