Are you a healthcare professional? Join GoodRx for HCPs

Compare Labetalol vs. Losartan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Labetalol
Losartan (Cozaar)
Labetalol
Losartan (Cozaar)
Summary of Labetalol vs. Losartan
Summary for Beta blocker
Prescription only
Labetalol is a medication that works as both an alpha blocker and beta blocker. It's used to treat high blood pressure in adults. But it's not a first-choice medication for blood pressure, except during pregnancy. Labetalol is typically taken by mouth twice a day. It can also be given through the veins by a healthcare professional, usually in a hospital setting, to treat dangerously high blood pressure. Common side effects of oral labetalol include dizziness and feeling tired. This medication is only available as a generic; brand name Trandate has been discontinued.
Summary for ARB
Prescription only
Losartan, also known by the brand name Cozaar, is a first-choice medication that's used to lower blood pressure. It's also shown to protect against stroke in certain people. In addition, this medication can slow down the worsening of kidney problems in certain people with diabetes. Losartan (Cozaar) belongs to the drug class called angiotensin II receptor blockers (ARBs). This medication is taken by mouth once daily and is available as a lower-cost generic. Side effects can include dizziness, fatigue, and upper respiratory infections.
Indications of Labetalol vs. Losartan
Indications for

•High blood pressure

Indications for

•High blood pressure

•Lower the risk of stroke in people with high blood pressure who have a thickened heart (left ventricular hypertrophy)

•Slow down the worsening of kidney problems in people with Type 2 diabetes and high blood pressure
Pros and Cons of Labetalol vs. Losartan
Pros and Const for Beta blocker
Pros

•Less likely to affect heart rate than other beta blockers

•Less likely to cause weight gain than other beta blockers

•Safe to take during pregnancy

Cons

•Causes higher risk of wheezing and breathing problems compared to selective beta-blockers

•Need to take twice a day (and three times a day for some people)

•Stopping the medication suddenly can worsen chest pain

Pros and Const for ARB
Pros

•A first-choice blood pressure medication, including for those with heart failure, diabetes, and kidney problems

•Taken once per day

•Can be taken by children as young as 6 years old

•Works similarly to angiotensin-converting enzyme (ACE) inhibitors, but with fewer side effects, like cough and swelling

Cons

•Might cause dizziness

•Might not work as well for Black people as other blood pressure medications do

•Not safe to use during pregnancy

•Can interact with medications like lithium and nonsteroidal anti-inflammatory drugs (NSAIDs)
Common Side Effects of Labetalol vs. Losartan
Common Side Effects for

•Dizziness (11%)

•Nausea (6%)

•Feeling tired (5%)

•Indigestion (3%)

•Stuffy nose (3%)

•Headache (2%)

Common Side Effects for

•Upper respiratory infection (e.g., common cold; 8%)

•Dizziness (3%)

•Stuffy nose (2%)

•Back pain (2%)
Warnings of Labetalol vs. Losartan
Common Side Effects for

•Liver injury

•Heart failure

•Worsening chest pain and heart attacks

•Risk of difficulty breathing

•Hiding symptoms of low blood sugar

•Greater risk during surgery

•Risk of heart block (medication interaction)

Common Side Effects for

•Harm to unborn baby

•Low blood pressure

•Kidney damage

•High potassium levels
Prices with our coupons for Labetalol vs. Losartan
Learn more about Labetalol
Learn more about Losartan

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.

Compare Labetalol vs. Losartan

Summary of Labetalol vs. Losartan

Indications of Labetalol vs. Losartan

Pros and Cons of Labetalol vs. Losartan

Common Side Effects of Labetalol vs. Losartan

Warnings of Labetalol vs. Losartan

Prices with our coupons for Labetalol vs. Losartan

Compare other Hypertension drugs

Browse medications

Good news for your inbox