Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Metoprolol tartrate (Lopressor) and clonidine (Catapres, Nexiclon XR) are both used to treat high blood pressure, but they belong to different medication classes and have distinct uses and side effects. Metoprolol is a beta blocker that also treats chest pain and lowers the risk of death after a heart attack. It is typically taken twice daily with food. Common side effects include dizziness and tiredness. Clonidine, an alpha agonist, can be taken as a tablet or used as a skin patch and is not usually a first-choice treatment for high blood pressure due to the risk of rebound hypertension if stopped suddenly. It can cause dry mouth, drowsiness, and dizziness. Clonidine is also not recommended for older adults because it increases the risk of falls. BOth medications are available in both generic and brand-name forms. Both medications require careful monitoring and should not be stopped abruptly without consulting a healthcare provider.
Metoprolol tartrate (Lopressor)
Clonidine
Metoprolol tartrate (Lopressor)
Clonidine
Summary of Lopressor vs. Catapres-TTS
Summary for Beta blocker
Prescription only
Metoprolol tartrate (Lopressor) is used to treat chest pain and high blood pressure. It's also used to lower the risk of death after a heart attack. This medication is taken by mouth, typically twice daily, though your dosage depends on what condition you have. Some side effects of metoprolol tartrate (Lopressor) include dizziness or tiredness. Metoprolol tartrate (Lopressor) is available as a brand name and generic tablet.
Summary for Alpha agonist
Prescription only
Clonidine is a prescription medication that can be used to treat high blood pressure. It comes in 3 forms: topical patch, immediate-release tablet, and extended-release tablet. Clonidine usually isn't a first-choice option to treat high blood pressure because it can cause "rebound hypertension" (sudden rise in blood pressure) when the medication is suddenly stopped. Clonidine also isn't recommended for older adults since it can raise the risk for falls.