Key takeaways
Metoprolol tartrate (Lopressor) and clonidine (Catapres, Nexiclon XR) are both used to treat high blood pressure, but they belong to different medication classes and have distinct uses and side effects. Metoprolol is a beta blocker that also treats chest pain and lowers the risk of death after a heart attack. It is typically taken twice daily with food. Common side effects include dizziness and tiredness. Clonidine, an alpha agonist, can be taken as a tablet or used as a skin patch and is not usually a first-choice treatment for high blood pressure due to the risk of rebound hypertension if stopped suddenly. It can cause dry mouth, drowsiness, and dizziness. Clonidine is also not recommended for older adults because it increases the risk of falls. BOth medications are available in both generic and brand-name forms. Both medications require careful monitoring and should not be stopped abruptly without consulting a healthcare provider.
