Key takeaways
Enalapril (Vasotec) and Felodipine ER (Plendil) are both medications used to treat high blood pressure, but they belong to different classes and work in distinct ways. Enalapril is an ACE inhibitor that relaxes blood vessels by blocking a protein called ACE, and it can also be used for heart failure. It is taken once or twice daily and is available in both pill and liquid forms. Common side effects include tiredness, dizziness, and a dry cough. Felodipine ER, on the other hand, is a calcium channel blocker that lowers blood pressure by relaxing blood vessels. It is typically taken once daily and is only available as a tablet. Side effects of Felodipine ER include swelling, headache, and flushing. Unlike Enalapril, Felodipine ER should be used with caution in people with heart failure. Enalapril can be taken with or without food, while Felodipine ER should be taken on an empty stomach or with a light meal. Both medications require a prescription and are not controlled substances.
