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Compare Enalapril vs. Plendil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Enalapril (Vasotec) and Felodipine ER (Plendil) are both medications used to treat high blood pressure, but they belong to different classes and work in distinct ways. Enalapril is an ACE inhibitor that relaxes blood vessels by blocking a protein called ACE, and it can also be used for heart failure. It is taken once or twice daily and is available in both pill and liquid forms. Common side effects include tiredness, dizziness, and a dry cough. Felodipine ER, on the other hand, is a calcium channel blocker that lowers blood pressure by relaxing blood vessels. It is typically taken once daily and is only available as a tablet. Side effects of Felodipine ER include swelling, headache, and flushing. Unlike Enalapril, Felodipine ER should be used with caution in people with heart failure. Enalapril can be taken with or without food, while Felodipine ER should be taken on an empty stomach or with a light meal. Both medications require a prescription and are not controlled substances.

  • Enalapril (Vasotec)
    Felodipine er (Plendil)
  • Enalapril (Vasotec)
    Felodipine er (Plendil)

  • Summary of Enalapril vs. Plendil

    Summary for ACE inhibitor
    Prescription only

    Enalapril (Vasotec) is a first-choice medication used for treating high blood pressure. It's also approved for heart failure. Enalapril (Vasotec) belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It's taken by mouth, once or twice daily. Enalapril (Vasotec) doesn't cause many side effects, but some include tiredness, dizziness, and cough.

    Summary for Calcium channel blocker (CCB)
    Prescription only

    Felodipine ER (Plendil) is a calcium channel blocker. It lowers blood pressure by relaxing your blood vessels. This medication is one of the first-choice options for treating high blood pressure in adults. It's taken by mouth, typically once daily. Some side effects of this medication include swelling, headache, and flushing. Brand name Plendil has been discontinued.

  • Indications of Enalapril vs. Plendil

    Indications for
    •High blood pressure
    •Heart failure
    Indications for
    •High blood pressure (hypertension)

  • Pros and Cons of Enalapril vs. Plendil

    Pros and Const for ACE inhibitor
    Pros
    •A first-choice blood pressure lowering medication for many people
    •Taken by mouth
    •Can be taken by children as young as 1 month old (high blood pressure only)
    •Available as a liquid for people who have trouble swallowing pills
    Cons
    •More likely to cause a dry cough, compared to angiotensin II receptor blockers (ARBs)
    •Can't be taken during pregnancy or breastfeeding
    •Might not work as well for lowering high blood pressure in black people
    •Need to take twice daily for heart failure
    Pros and Const for Calcium channel blocker (CCB)
    Pros
    •Taken by mouth
    •Taken once daily
    •Available as a lower-cost generic medication
    Cons
    •Only available as a tablet
    •Not a good choice if you've heart failure
    •Not recommended in pregnancy

  • Common Side Effects of Enalapril vs. Plendil

    Common Side Effects for
    •Feeling tired (3%)
    Common Side Effects for
    •Swelling in the arms, hands, legs, or feet (up to 17%)
    •Headache (up to 15%)
    •Flushing (up to 7%)

  • Warnings of Enalapril vs. Plendil

    Common Side Effects for
    •Not for use during pregnancy
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Heart problems due to high potassium
    •Liver problems
    Common Side Effects for
    •Severely low blood pressure
    •Caution with heart failure
    •Swelling

  • Prices with our coupons for Enalapril vs. Plendil

    Learn more about Enalapril
    Learn more about Felodipine er

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