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Enalapril vs. Sular

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Enalapril (Vasotec, Epaned) and nisoldipine (Sular) are both medications used to treat high blood pressure. However, they belong to different medication classes. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor, while nisoldipine is a calcium channel blocker (CCB). Enalapril is also FDA-approved for treating heart failure, whereas nisoldipine is not. Enalapril can be taken once or twice daily, and it is available in both tablet and liquid forms, making it suitable for children as young as 1 month old. Nisoldipine is taken once daily as an extended-release tablet on an empty stomach. Common side effects of enalapril include tiredness, dizziness, and cough, while nisoldipine may cause swelling in the legs and feet and headaches. Enalapril can interact with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Motrin, Advil), whereas nisoldipine interacts with grapefruit and several other medications. Both medications require a prescription and are not controlled substances.

Enalapril

(Vasotec)

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Nisoldipine

(Sular)

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Summary for Enalapril

Prescription only

Enalapril (Vasotec) is a first-choice medication used for treating high blood pressure. It's also approved for heart failure. Enalapril (Vasotec) belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It's taken by mouth, once or twice daily. Enalapril (Vasotec) doesn't cause many side effects, but some include tiredness, dizziness, and cough.

Indications for Enalapril

  • High blood pressure
  • Heart failure

Pros and Cons for Enalapril

Pros

  • A first-choice blood pressure lowering medication for many people
  • Taken by mouth
  • Can be taken by children as young as 1 month old (high blood pressure only)
  • Available as a liquid for people who have trouble swallowing pills

Cons

Common Side Effects for Enalapril

  • Feeling tired (3%)

Warnings for Enalapril

  • Not for use during pregnancy
  • Angioedema (swelling)
  • Low blood pressure
  • Worsening kidney problems
  • Heart problems due to high potassium
  • Liver problems

Summary for Sular

Prescription only

Nisoldipine (Sular) is a type of blood pressure medication called a calcium channel blocker. It treats high blood pressure (hypertension) in adults. The extended-release tablets are taken by mouth once per day on an empty stomach. Some side effects include swelling in the arms or legs and headache. Nisoldipine (Sular) is available as a brand-name and generic medication.

Indications for Sular

Pros and Cons for Sular

Pros

Cons

Common Side Effects for Sular

  • Swelling in the legs, feet, or hands (22%)
  • Headache (22%)

Warnings for Sular

  • Severely low blood pressure
  • Risk of heart attack and chest pain
  • Allergic reaction

Prices with our coupons for Enalapril vs. Sular

Price Card Drug Icon
Enalapril60 tablets / 20mg
$17.20$53.10
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Price Card Drug Icon
Nisoldipine90 tablets / 8.5mg
$151.25$738.62
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