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Compare Enalapril vs. Sular

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Enalapril (Vasotec, Epaned) and nisoldipine (Sular) are both medications used to treat high blood pressure. However, they belong to different medication classes. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor, while nisoldipine is a calcium channel blocker (CCB). Enalapril is also FDA-approved for treating heart failure, whereas nisoldipine is not. Enalapril can be taken once or twice daily, and it is available in both tablet and liquid forms, making it suitable for children as young as 1 month old. Nisoldipine is taken once daily as an extended-release tablet on an empty stomach. Common side effects of enalapril include tiredness, dizziness, and cough, while nisoldipine may cause swelling in the legs and feet and headaches. Enalapril can interact with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Motrin, Advil), whereas nisoldipine interacts with grapefruit and several other medications. Both medications require a prescription and are not controlled substances.

  • Enalapril (Vasotec)
    Nisoldipine (Sular)
  • Enalapril (Vasotec)
    Nisoldipine (Sular)

  • Summary of Enalapril vs. Sular

    Summary for ACE inhibitor
    Prescription only

    Enalapril (Vasotec) is a first-choice medication used for treating high blood pressure. It's also approved for heart failure. Enalapril (Vasotec) belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It's taken by mouth, once or twice daily. Enalapril (Vasotec) doesn't cause many side effects, but some include tiredness, dizziness, and cough.

    Summary for Calcium channel blocker (CCB)
    Prescription only

    Nisoldipine (Sular) is a type of blood pressure medication called a calcium channel blocker. It treats high blood pressure (hypertension) in adults. The extended-release tablets are taken by mouth once per day on an empty stomach. Some side effects include swelling in the arms or legs and headache. Nisoldipine (Sular) is available as a brand-name and generic medication.

  • Indications of Enalapril vs. Sular

    Indications for
    •High blood pressure
    •Heart failure
    Indications for
    •High blood pressure (hypertension)

  • Pros and Cons of Enalapril vs. Sular

    Pros and Const for ACE inhibitor
    Pros
    •A first-choice blood pressure lowering medication for many people
    •Taken by mouth
    •Can be taken by children as young as 1 month old (high blood pressure only)
    •Available as a liquid for people who have trouble swallowing pills
    Cons
    •More likely to cause a dry cough, compared to angiotensin II receptor blockers (ARBs)
    •Can't be taken during pregnancy or breastfeeding
    •Might not work as well for lowering high blood pressure in black people
    •Need to take twice daily for heart failure
    Pros and Const for Calcium channel blocker (CCB)
    Pros
    •Taken by mouth once daily
    •Can take together with other blood pressure medications
    Cons
    •Can cause headache and swelling in the legs and feet
    •Interacts with grapefruit and many other medications, such as amiodarone (Pacerone) and ketoconazole

  • Common Side Effects of Enalapril vs. Sular

    Common Side Effects for
    •Feeling tired (3%)
    Common Side Effects for
    •Swelling in the legs, feet, or hands (22%)
    •Headache (22%)

  • Warnings of Enalapril vs. Sular

    Common Side Effects for
    •Not for use during pregnancy
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Heart problems due to high potassium
    •Liver problems
    Common Side Effects for
    •Severely low blood pressure
    •Risk of heart attack and chest pain
    •Allergic reaction

  • Prices with our coupons for Enalapril vs. Sular

    Learn more about Enalapril
    Learn more about Nisoldipine

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