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Nisoldipine Coupon - Nisoldipine 17mg tablet

nisoldipine

Generic Sular
Used for Hypertension
Used for Hypertension

Nisoldipine (Sular) is a type of blood pressure medication called a calcium channel blocker. It treats high blood pressure (hypertension) in adults. The extended-release tablets are taken by mouth once per day on an empty stomach. Some side effects include swelling in the arms or legs and headache. Nisoldipine (Sular) is available as a brand-name and generic medication.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on January 15, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Nisoldipine (Sular)?

What is Nisoldipine (Sular) used for?

How Nisoldipine (Sular) works

Nisoldipine (Sular) is a calcium channel blocker. It works by relaxing your blood vessels to lower your blood pressure.

Are you looking for information on nifedipine (Procardia XL) or nimodipine (Nymalize) instead?
When does Nisoldipine (Sular) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Full effect

Drug Facts

Common BrandsSular
Drug ClassCalcium channel blocker (CCB)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Nisoldipine (Sular) essentials

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Written by Stacia Woodcock, PharmD
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What are the side effects of Nisoldipine (Sular)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Swelling in the legs, feet, or hands (22%)
  • Headache (22%)

Other Side Effects

  • Dizziness
  • Heart palpitation (feeling that your heart is racing)
  • Chest pain
  • Sore throat
  • Sinus infection
  • Nausea
  • Rash

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
  • Heart attack or severe chest pain: tightness and pain in the chest, neck, arms, or back; anxiety; dizziness; tiredness; cold and clammy skin; sweating; heartburn; nausea,

Source: DailyMed

More on Nisoldipine (Sular) side effects

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The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloating or swelling of face, arms, hands, lower legs, or feet

rapid weight gain

tingling of hands or feet

unusual weight gain or loss

Less common

Chest pain

dizziness, lightheadedness, or fainting

fast, irregular, pounding, or racing heartbeat or pulse

feeling of warmth or heat

flushing or redness of skin, especially on face and neck

headache

rash

sweating

Rare

Chest tightness

shortness of breath

swelling of the arms, face, legs, lips, tongue, or throat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Body aches or pain

congestion

cough

dryness or soreness of throat

fever

heartbeat sensations

hoarseness

pain or tenderness around eyes and cheekbones

runny nose

stuffy nose

tender, swollen glands in neck

trouble in swallowing

voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Nisoldipine (Sular)

thumbs-up

Pros

Taken by mouth once daily

Can take together with other blood pressure medications

thumbs-down

Cons

Can cause headache and swelling in the legs and feet

Interacts with grapefruit and many other medications, such as amiodarone (Pacerone) and ketoconazole

pharmacist-tips

Pharmacist tips for Nisoldipine (Sular)

pharmacist

  • Take nisoldipine (Sular) on an empty stomach, at least 1 hour before or 2 hours after a meal. Taking it with food can lower the amount of medication that gets absorbed into your body.

    • Swallow the nisoldipine (Sular) tablet whole. Don't chew, break, or crush them since the medication might not work as well and might cause more side effects. If you can't swallow the tablets whole, talk to your prescriber about possibly switching to a different medication.

      • It typically takes about a few weeks or so before you can see the full effects of nisoldipine (Sular) on your blood pressure. Don't worry if you don't see a change in your blood pressure right after you start taking the medication.

        • Check your blood pressure regularly at home as you continue to take nisoldipine (Sular) every day. Write down your blood pressure measurements and share them with your prescriber. Your prescriber will use these measurements to recommend any needed dose adjustments.

          • You might feel dizzy when you first start taking nisoldipine (Sular) and when your dose gets raised. This feeling often happens when you stand up. Be sure to get up slowly or hold onto something to prevent dizziness. You should feel less dizzy as you continue taking the medication and as you get used to your new blood pressure.

            • It's common to have swelling in your feet, ankles, legs, or hands when you take nisoldipine (Sular). Some ways to ease the swelling include sitting or lying down with your legs raised and wearing compression socks. Talk with your prescriber for more tips on how to manage swelling from this medication.

              • Avoid grapefruit and grapefruit juice while you're taking nisoldipine (Sular). It can make the levels of the medication in your body become too high. This can raise your risk of side effects.

                • Tell your prescriber and pharmacist about all the over-the-counter and prescription medications that you're taking. Nisoldipine (Sular) can interact with many medications, such as certain antifungals, clarithromycin, and carbamazepine (Tegretol). Your care team can check that your medications are safe to take together.

                  • Don't lower your nisoldipine (Sular) dose or stop taking the medication suddenly without talking to your prescriber first. Otherwise, it can cause your blood pressure to rise quickly.

                    More on Nisoldipine (Sular) tips

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                    faqs

                    Frequently asked questions about Nisoldipine (Sular)

                    When is the best time to take nisoldipine (Sular)?
                    In general, there isn't any particular time of day that blood pressure medications like nisoldipine (Sular) work best. Keep in mind that you should take nisoldipine (Sular) on an empty stomach, at least 1 hour before or 2 hours after a meal. Choose a time that's most convenient for you and easiest for you to remember so you don't miss any doses. Remember to take nisoldipine (Sular) consistently at the same time every day so it can work as best as possible for you.
                    Can I take naproxen (Aleve) with nisoldipine (Sular)?
                    It's okay to take naproxen (Aleve) with nisoldipine (Sular). But nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen (Aleve) aren't the best choice for everyone because they can have risky side effects. Don't take naproxen (Aleve) without talking to a healthcare professional first, especially if you have kidney or heart problems.
                    Can I take acetaminophen (Tylenol) with nisoldipine (Sular)?
                    In general, most people can take acetaminophen (Tylenol) with nisoldipine (Sular). These two medications don't interact with each other or affect how well each works. Keep in mind that acetaminophen (Tylenol) has a risk of causing liver damage. So this pain reliever might not the best choice for everyone. Ask a healthcare professional whether acetaminophen (Tylenol) is safe for you to take, especially if you have a history of liver problems or if you take other medications that affect the liver.
                    Does nisoldipine (Sular) cause weight gain?
                    Weight gain isn't a typical side effect of calcium channel blockers like nisoldipine (Sular). Only up to 1% of people reported having weight gain while they were taking nisoldipine (Sular). But it's not clear if it was really from the medication. Keep in mind that a common side effect of nisoldipine (Sular) is swelling from fluid buildup. This can look like weight gain. Let your primary care provider or cardiologist know if you notice unusual or unexpected weight gain while you're taking nisoldipine (Sular). They can try to help you figure out what's causing this weight gain.
                    What's the difference between nisoldipine (Sular) and nifedipine (Procardia)?
                    Nisoldipine (Sular) and nifedipine (Procardia) are blood pressure medications called calcium channel blockers. They have similar side effects. They both have extended-release versions that are taken once per day. But nifedipine (Procardia) also comes as an immediate-release tablet that's taken three times per day. Another difference is that you should take nisoldipine (Sular) on an empty stomach. But it doesn't matter whether you take nifedipine (Procardia) with or without food. Talk to your prescriber if you have more questions about the differences between both medications.
                    Is nisoldipine (Sular) a narcotic?
                    No, nisoldipine (Sular) isn't a narcotic. The term "narcotic" typically refers to opioid medications. And nisoldipine (Sular) isn't an opioid.
                    Can I take nisoldipine (Sular) if I have heart failure?
                    Speak with your prescriber if you have heart failure. It's not clear how safe nisoldipine (Sular) is for people with heart failure. Your prescriber will weigh the risks and benefits of treatment. They might follow up with you more often if you take nisoldipine (Sular), especially if you're also taking a beta blocker like metoprolol succinate (Toprol XL).
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                    What are the risks and warnings for Nisoldipine (Sular)?

                    Nisoldipine (Sular) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                    risk-warning

                    Severely low blood pressure

                    Nisoldipine (Sular) can sometimes cause your blood pressure to drop too much. It can make you feel dizzy, tired, or lightheaded. This side effect commonly happens when you start taking the medication and when your dose gets raised.

                    If your blood pressure drops too much and you feel too dizzy, make sure to sit down slowly while holding onto something stable. Let your prescriber know because they might need to adjust the dose of your medication. Get medical help right away if you fall and hit your head.

                    risk-warning

                    Risk of heart attack and chest pain

                    • Risk factors: Severe coronary artery disease

                      Although rare, it's possible for some people to have worsening chest pain or have a heart attack while they're taking nisoldipine (Sular). The risk is higher if you have a heart problem called coronary artery disease (CAD). The risk for worsening chest pain or heart attack can appear when you first start taking this medication and when your dose gets raised.

                      Get medical help right away if you experience dizziness, anxiety, chest pain, pressure in the chest, shortness of breath, or nausea. These can be signs of chest pain or heart attack.

                      risk-warning

                      Allergic reaction

                      • Risk factors: History of allergy to FD&C Yellow No. 5 (tartrazine)

                        Certain versions of nisoldipine (Sular) might contain a dye called FD&C Yellow No. 5 (tartrazine). Although rare, some people can have an allergic reaction to this ingredient.

                        Get medical help right away if you have hives, itching, or other signs of an allergic reaction after you take nisoldipine (Sular).

                        dosage

                        Nisoldipine (Sular) dosage forms

                        The average cost for 90 tablets of 17mg of Nisoldipine (Sular) is $92.13 with a free GoodRx coupon. This is 83.3% off the average retail price of $551.53.
                        tablet
                        Tablet
                        DosageQuantityPrice as low asPrice per unit
                        8.5mg30 tablets$31.11$1.04
                        17mg90 tablets$92.13$1.02
                        20mg5 tablets$15.29$3.06
                        25.5mg30 tablets$39.72$1.32
                        30mg30 tablets$74.67$2.49
                        34mg30 tablets$32.80$1.09
                        40mg30 tablets$71.67$2.39

                        Typical dosing for Nisoldipine (Sular)

                        The typical starting dose is 17 mg by mouth once daily on an empty stomach (at least 1 hour before or 2 hours after a meal). Your starting dose might differ if you're over 65 years old or if you have liver problems.

                        Your prescriber will adjust the dose based on how well the medication is working to control your blood pressure and whether you're having bothersome side effects.

                        The maximum dose is 34 mg by mouth per day.

                        interactions

                        Interactions between Nisoldipine (Sular) and other drugs

                        Nisoldipine (Sular) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Nisoldipine (Sular). Please note that only the generic name of each medication is listed below.

                        Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                        Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        drug-cost

                        How much does Nisoldipine (Sular) cost?

                        To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                        Sular (brand)
                        GoodRx lowest price

                        $15.29

                        (save 99.55%)
                        Nisoldipine (Sular) (generic)
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                        contraindications-icon

                        Nisoldipine (Sular) contraindications

                        Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Nisoldipine (Sular) will not be safe for you to take.
                        alternatives

                        What are alternatives to Nisoldipine (Sular)?

                        There are a number of medications that your doctor can prescribe in place of Nisoldipine (Sular). Compare a few possible alternatives below.
                        Nisoldipine (Sular)
                        Used for:
                        $15.29 Lowest GoodRx priceView Prices
                        Isradipine
                        Used for:

                        • High blood pressure (hypertension)

                        $109.22 Lowest GoodRx priceView Prices
                        Nifedipine ER (Procardia XL)
                        Used for:

                        • Chest pain (angina)

                        • High blood pressure (hypertension) - extended-release tablets only

                        $9.30 Lowest GoodRx priceView Prices
                        images

                        Nisoldipine (Sular) images

                        Yellow Round M And Ne 17 - Nisoldipine 17mg Extended-Release Tablet
                        This medicine is Yellow, Round Tablet Imprinted With "Ne 17" And "M".Yellow Round M And Ne 17 - Nisoldipine 17mg Extended-Release Tablet
                        Yellow Round Sci 501 - Nisoldipine 17mg Extended-Release Tablet
                        This medicine is Yellow, Round Tablet Imprinted With "Sci 501".Yellow Round Sci 501 - Nisoldipine 17mg Extended-Release Tablet

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                        References

                        Best studies we found

                        Covid Pharma US, Inc. (2023). Sular- nisoldipine tablet, film coated, extended release [package insert]. DailyMed.

                        Preuss, C. V., et al. (2023). Prescription of controlled substances: Benefits and risks. StatPearls.

                        U.S. Food and Drug Administration. (2023). How safe are color additives?

                        GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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