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Nimodipine Coupon - Nimodipine 30mg capsule

nimodipine

Generic Nymalize
Used for Hemorrhage
Used for Hemorrhage

Nimodipine (Nymalize) is used to help prevent brain damage after an aneurysmal subarachnoid hemorrhage (a type of brain bleed). Your provider will typically start this medication in the hospital as soon as possible, but usually within 4 days of a subarachnoid hemorrhage. Nimodipine (Nymalize) is taken by mouth or given through a feeding tube every 4 hours for 3 weeks. Generic nimodipine comes as an oral capsule, while brand name Nymalize (nimodipine) comes as an oral liquid. The most common side effect of nimodipine (Nymalize) is low blood pressure, so your provider will check your blood pressure regularly while you're taking this medication.

Last reviewed on April 24, 2023
basics-icon

What is Nimodipine (Nymalize)?

What is Nimodipine (Nymalize) used for?

  • Prevention of brain damage after a type of brain bleed called an aneurysmal subarachnoid hemorrhage (aSAH)

How Nimodipine (Nymalize) works

Nimodipine (Nymalize) is a calcium channel blocker. The exact way it works to help people after a brain bleed isn't known. But it's thought to relax the blood vessels in your brain to maintain blood flow and possibly prevent vasospasm. This helps to prevent further damage to the brain after a subarachnoid hemorrhage.

Drug Facts

Common BrandsNymalize
Drug ClassCalcium channel blocker (CCB)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$1407.45(save 94.94%)
GoodRx discount
$71.24
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What are the side effects of Nimodipine (Nymalize)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low blood pressure (4%)
  • Diarrhea (2%)
  • Rash (2%)
  • Stomach irritation (2%)

Other Side Effects

  • Headache
  • Nausea
  • Slow heartbeat

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blurred vision

chest pain or discomfort

confusion

difficult or labored breathing

fast, pounding, or irregular heartbeat or pulse

lightheadedness, dizziness, or fainting

shortness of breath

slow or irregular heartbeat

sweating

swelling

tightness in the chest

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal or stomach cramps, discomfort, or pain

back pain

blemishes on the skin

constipation

diarrhea

discouragement

feeling sad or empty

headache

indigestion

irritability

lack or loss of appetite

loss of interest or pleasure

muscle pain

nausea or vomiting

pimples

rash

swollen mouth and tongue

tiredness

trouble concentrating

trouble sleeping

unpleasant taste

urge to have bowel movement

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Nimodipine (Nymalize)

thumbs-up

Pros

Prevents worsening of brain function after brain bleed

Available in liquid form if you can't swallow the capsule

Treatment typically lasts 3 weeks

Low risk of serious side effects

thumbs-down

Cons

Can interact with some common medications and supplements

Needs to be taken every 4 hours

Needs to be taken on an empty stomach

Can lower blood pressure and cause dizziness

pharmacist-tips

Pharmacist tips for Nimodipine (Nymalize)

pharmacist
  • Swallow nimodipine (Nymalize) capsules whole. If you're having trouble swallowing the capsules, contact your provider. They might be able to recommend other options for you, such as nimodipine (Nymalize) oral solution.

    • Take nimodipine (Nymalize) at least 1 hour before or 2 hours after a meal. It might be helpful to plan your meals since you need to take this medication every 4 hours.

      • Make sure your medical team knows all the medications you're currently taking as soon as possible. This is because some medications, including the ones you might restart after you leave the hospital, can interact with nimodipine (Nymalize). For example, antibiotics like azithromycin (Zithromax) and fluconazole (Diflucan) can raise the level of nimodipine (Nymalize) in your body. Taking these medications together can raise your risk for side effects, like low blood pressure.

        • Avoid grapefruit or grapefruit juice while taking nimodipine (Nymalize) because it can raise the amount of the medication in your body, which raises your risk of side effects.

          More tips for Nymalize (nimodipine) liquid only

          • If giving Nymalize (nimodipine) through a feeding tube, carefully flush the feeding tube after each dose with 10 mL of saline solution to make sure that all of the medication gets into the stomach. Never administer nimodipine (Nymalize) as an injection into the veins due to risk of severe and life-threatening harm.

            • Only use the oral syringe that comes with the medication to measure out your dose. Don't use household spoons because they aren't accurate and might cause you to take the wrong dose.

              faqs

              Frequently asked questions about Nimodipine (Nymalize)

              What is an aneurysmal subarachnoid hemorrhage (aSAH)?
              An aneurysmal subarachnoid hemorrhage (aSAH) is a type of brain bleed. It happens when an aneurysm on an artery around the brain has bursted open, causing bleeding around the brain. After an aSAH, the blood vessels in your brain can squeeze (called a vasospasm), which can cause because your brain isn't getting enough blood. While the exact way nimodipine (Nymalize) works to prevent further damage in the brain isn't known, it's thought to help by keeping your blood vessels open so blood can reach your brain.
              When is nimodipine (Nymalize) used for people with aneurysmal subarachnoid hemorrhage (aSAH)?
              The American Heart Association treatment guideline recommends nimodipine (Nymalize) for all people who diagnosed with an aSAH because it's been shown to help brain health and outcomes. This medication is typically started as soon as possible after or within 4 days of an aSAH.
              Does nimodipine (Nymalize) lower blood pressure?
              Yes, low blood pressure is one of the more common side effects of nimodipine (Nymalize). When you start this medication, your healthcare team will check your blood pressure regularly to make sure it doesn't drop too low. If you're discharged from the hospital with nimodipine (Nymalize), it's likely your provider will ask you to continue to check your blood pressure at home. Be especially careful if you're also taking other medications that can lower blood pressure. Let your provider know right away if you experience symptoms of dangerously low blood pressure, such as dizziness, nausea, or blurry vision. They can let you know if you need more medical attention.
              Does nimodipine (Nymalize) affect heart rate?
              When taken by mouth at recommended doses, it's very unlikely for nimodipine (Nymalize) to affect your heart rate. However, in rare cases, nimodipine (Nymalize) some people have reported high or low heart rates after taking this medication. Let your provider know right away if you feel symptoms of abnormal heart rate, such as feeling faint, chest pain, or trouble breathing.
              Can nimodipine (Nymalize) capsules be crushed and opened?
              No, don't crush or cut open the nimodipine (Nymalize) capsules. The manufacturers of nimodipine (Nymalize) say that, if needed, you can pull the liquid out of the capsule using a medical needle and syringe, then take the contents by mouth with an oral syringe. But the process of pulling the liquid out of the nimodipine (Nymalize) capsule can be inconvenient. If you can't swallow capsules or take medication by mouth, talk with your provider. They might recommend brand name Nymalize (nimodipine), which is a liquid form of nimodipine, for you. Nymalize (nimodipine) might be more convenient to take for people who can't swallow the capsules and can also be given through a feeding tube.
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              What are the risks and warnings for Nimodipine (Nymalize)?

              Nimodipine (Nymalize) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Take by mouth only

              Nimodipine (Nymalize) should only be given by mouth or in a feeding tube. Never inject nimodipine (Nymalize) into the veins because this can cause very serious and life-threatening heart and blood pressure

              risk-warning

              Low blood pressure

              • Risk factors: Taking other medications that lower blood pressure | Not enough fluid in your body | Having diarrhea or vomiting for a long time | Low salt levels in your body

                Sometimes, taking nimodipine (Nymalize) can cause your blood pressure to drop too much. This can cause you to feel dizzy, tired, or lightheaded. Because of this, your provider will check your blood pressure regularly while you're taking nimodipine (Nymalize) at the hospital. Continue to check your blood pressure regularly after you're discharge from your hospital stay. To lower your risk of falls, sit down slowly while holding onto something stable. If you fall and hit your head, get medical help right away. If the dizziness is very bothersome or if you have other symptoms of low blood pressure, such as blurry vision or nausea, talk to your provider.

                risk-warning

                Medication interactions

                Make sure your medical team knows all the medications you're currently taking as soon as possible. This is because some medications, including the ones you might restart after you leave the hospital, can interact with nimodipine (Nymalize). For example, certain antibiotics or antivirals, such as clarithromycin (Biaxin) and ritonavir (Norvir) can raise the level of nimodipine (Nymalize) in your body, which can put you at higher risk for dangerously low blood pressure. Another example is that certain medications, such as carbamazepine (Tegretol) or phenytoin (Dilantin), can lower the level of nimodipine (Nymalize) in your body and cause it to not work as well. Ask your medical team to review all your current medications before you leave the hospital to make sure that there aren't any serious interactions with nimodipine (Nymalize).

                dosage

                Nimodipine (Nymalize) dosage forms

                The average cost for 90 capsules of 30mg of Nimodipine (Nymalize) is $71.24 with a free GoodRx coupon. This is 94.94% off the average retail price of $1407.45.
                bottle of oral solution
                Bottle of oral solution
                DosageQuantityPrice as low asPrice per unit
                473ml of 3mg/ml1 bottle$1192.31$1192.31
                capsule
                Capsule
                DosageQuantityPrice as low asPrice per unit
                30mg90 capsules$71.24$0.79

                Typical dosing for Nimodipine (Nymalize)

                Your provider will start nimodipine (Nymalize) for you as soon as possible, but within 4 days of a subarachnoid hemorrhage.

                • The typical dose is 60 mg by mouth every 4 hours for 3 weeks.

                Your dose might be different if you've liver problems.

                interactions

                Interactions between Nimodipine (Nymalize) and other drugs

                Nimodipine (Nymalize) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Nimodipine (Nymalize). Please note that only the generic name of each medication is listed below.

                Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                Nimodipine (Nymalize) images

                White Ani 210 - Nimodipine 30mg Capsule
                This medicine is White Capsule Imprinted With "Ani 210".White Ani 210 - Nimodipine 30mg Capsule
                White Ani 210 - Nimodipine 30mg Capsule
                This medicine is White Capsule Imprinted With "Ani 210".White Ani 210 - Nimodipine 30mg Capsule
                White Ani 210 - Nimodipine 30mg Capsule
                This medicine is White Capsule Imprinted With "Ani 210".White Ani 210 - Nimodipine 30mg Capsule

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                References

                Best studies we found

                American Heart Association. (2016). Low blood pressure – when blood pressure is too low.

                American Heart Association. (2021). What is an aneurysm?

                Azurity Pharmaceuticals. (2023). Nymalize [package insert]. DailyMed.

                View All References (6)

                Bauer, A. M., et al. (2014). Treatment of intracranial vasospasm following subarachnoid hemorrhage. Frontiers in Neurology.

                Chong, J. Y. (2022). Subarachnoid hemorrhage (SAH). Merck Manual Professional Version. 

                Connolly Jr., E. S., et al. (2012). Guidelines for the management of aneurysmal subarachnoid hemorrhage. Stroke.

                D'Souza, S. (2015). Aneurysmal subarachnoid hemorrhage. Journal of Neurosurgical Anesthesiology.

                Hao, G., et al. (2022). Clinical effectiveness of nimodipine for the prevention of poor outcome after aneurysmal subarachnoid hemorrhage: A systematic review and meta-analysis. Frontiers in Neurology.

                U.S. Food and Drug Administration. (2021). Grapefruit juice and some drugs don't mix.

                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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