Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Felodipine ER (Plendil) and nisoldipine (Sular) are both calcium channel blockers used to treat high blood pressure. Felodipine ER is typically taken once daily in doses ranging from 2.5 mg to 10 mg, while nisoldipine is also taken once daily but in higher doses, starting at 17 mg and going up to 34 mg. Felodipine ER is available only as a generic, whereas nisoldipine is available both as a brand (Sular) and a generic. Common side effects for both medications include swelling, headaches, and dizziness. Felodipine ER can be taken with or without food, but nisoldipine should be taken on an empty stomach. Neither medication should not be crushed or chewed. Felodipine ER can be a first-choice option for treating high blood pressure, while nisoldipine is noted to be more expensive than many other alternatives.
Felodipine er (Plendil)
Nisoldipine (Sular)
Felodipine er (Plendil)
Nisoldipine (Sular)
Summary of Plendil vs. Sular
Summary for Calcium channel blocker (CCB)
Prescription only
Felodipine ER (Plendil) is a calcium channel blocker. It lowers blood pressure by relaxing your blood vessels. This medication is one of the first-choice options for treating high blood pressure in adults. It's taken by mouth, typically once daily. Some side effects of this medication include swelling, headache, and flushing. Brand name Plendil has been discontinued.
Summary for Calcium channel blocker (CCB)
Prescription only
Nisoldipine (Sular) is a type of blood pressure medication called a calcium channel blocker. It treats high blood pressure (hypertension) in adults. The extended-release tablets are taken by mouth once per day on an empty stomach. Some side effects include swelling in the arms or legs and headache. Nisoldipine (Sular) is available as a brand-name and generic medication.