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Plendil vs. Coreg

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Felodipine ER (Plendil) and carvedilol (Coreg) are both used to treat high blood pressure, but they belong to different medication classes and have different uses. Felodipine ER is a calcium channel blocker that works by relaxing your blood vessels, and it's typically taken once daily. Carvedilol, on the other hand, is a beta blocker that not only lowers blood pressure by relaxing blood vessels but also slows down your heart rate. Carvedilol is used for additional conditions like heart failure and reducing the risk of death after a heart attack. It comes in both immediate-release tablets taken twice daily and extended-release capsules taken once daily. Felodipine ER is generally not recommended for people with heart failure, while carvedilol should be avoided if you have asthma or certain heart conditions. Both medications are available as lower-cost generics, but they have different side effects and precautions. For example, felodipine ER can cause swelling and headaches, while carvedilol can cause dizziness, tiredness, and may hide symptoms of low blood sugar in people with diabetes.

Felodipine ER

(Plendil)

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Carvedilol

(Coreg)

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Summary for Plendil

Prescription only

Felodipine ER (Plendil) is a calcium channel blocker. It lowers blood pressure by relaxing your blood vessels. This medication is one of the first-choice options for treating high blood pressure in adults. It's taken by mouth, typically once daily. Some side effects of this medication include swelling, headache, and flushing. Brand name Plendil has been discontinued.

Indications for Plendil

Pros and Cons for Plendil

Pros

  • Taken by mouth
  • Taken once daily
  • Available as a lower-cost generic medication

Cons

  • Only available as a tablet
  • Not a good choice if you've heart failure
  • Not recommended in pregnancy

Common Side Effects for Plendil

  • Swelling in the arms, hands, legs, or feet (up to 17%)
  • Headache (up to 15%)
  • Flushing (up to 7%)

Warnings for Plendil

  • Severely low blood pressure
  • Caution with heart failure
  • Swelling

Summary for Coreg

Prescription only

Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

Indications for Coreg

  • High blood pressure
  • Heart failure
  • Lower the risk of death from heart-related problems after a heart attack

Pros and Cons for Coreg

Pros

  • Taken by mouth
  • Comes as a once-daily extended-release formulation
  • Dose can be adjusted based on your response
  • Available as a lower-cost generic

Cons

  • Need to take with food
  • Can cause you to feel more tired
  • Can cause dry eyes if you wear contact lenses
  • Shouldn't be taken if you have asthma or an asthma-related condition

Common Side Effects for Coreg

  • Dizziness (6%)

Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

Warnings for Coreg

  • Worsening chest pain and heart attacks
  • Slow heart rate and low blood pressure
  • Heart failure
  • Hiding symptoms of low blood sugar
  • Risk of difficulty breathing
  • Hiding symptoms of high thyroid hormone
  • Risk of kidney problems
  • Severe allergic reactions
  • Greater risk during surgery
  • Risk of eye problems during surgery

Prices with our coupons for Plendil vs. Coreg

Price Card Drug Icon
Felodipine ER90 tablets / 10mg
$26.90-
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Carvedilol180 tablets / 25mg
$20.25$223.12
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