Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Fosinopril (generic, brand name Monopril no longer available) and trandolapril (generic, brand name Mavik no longer available) are both ACE inhibitors used to treat high blood pressure and heart failure. Both medications also protect the kidneys in people with diabetes. Fosinopril is typically started at 10 mg and increased to 20 mg to 40 mg once daily, whereas trandolapril starts at 1 mg to 2 mg once daily, with a maximum dose of 8 mg. Both medications can cause a dry cough and dizziness, but trandolapril has a higher incidence of these side effects. Additionally, trandolapril is more likely to cause high uric acid levels. Both medications require regular blood tests to monitor kidney health and potassium levels. Neither should be taken during pregnancy due to the risk of birth defects.
Fosinopril
Trandolapril
Fosinopril
Trandolapril
Summary of Monopril vs. Mavik
Summary for ACE inhibitor
Prescription only
Fosinopril sodium (Monopril) is an angiotensin-converting enzyme (ACE) inhibitor. It's used to treat high blood pressure in adults and children. It can also treat heart failure. Fosinopril comes as a tablet that's taken by mouth once daily. Most people don't experience any side effects from fosinopril. But people who did reported cough and dizziness. Though rare, fosinopril and other ACEI inhibitors can cause angioedema, which can be serious. Brand name Monopril has been discontinued; fosinopril is only available as a generic medication.
Summary for ACE inhibitor
Prescription only
Trandolapril is a prescription medication that's used to treat high blood pressure (hypertension). It's also used to lower the risk of death and hospitalization in people with heart failure after a heart attack. Trandolapril is taken by mouth, typically once daily. Although the brand name for this medication (Mavik) has been discontinued, trandolapril is available as a lower-cost generic tablet. Common side effects include dry cough and dizziness.
Please note: The side effects above were reported by people taking this medication to lower the risk of death and hospitalization in certain heart failures after recent heart attack.
Warnings of Monopril vs. Mavik
Common Side Effects for
•Not safe during pregnancy
•Angioedema (swelling) and serious allergic reactions