Key takeaways
Losartan (Cozaar) and metoprolol tartrate (Lopressor) are both medications used to treat high blood pressure, but they belong to different drug classes. Losartan is an angiotensin II receptor blocker (ARB), while metoprolol tartrate is a beta blocker. Losartan is also used to lower the risk of stroke in people with high blood pressure and thickened heart walls (left ventricular hypertrophy), and to slow kidney problems in people with Type 2 diabetes. Metoprolol tartrate, on the other hand, is used to treat chest pain and to lower the risk of death after a heart attack. Losartan is typically taken once a day, whereas metoprolol tartrate is usually taken twice a day with food. Both medications are available in lower-cost generic forms. Common side effects of losartan include dizziness and upper respiratory infections, while metoprolol tartrate can cause tiredness as well as dizziness. Losartan can interact with nonsteroidal anti-inflammatory drugs (NSAIDs) and medications that raise potassium levels, while metoprolol tartrate can interact with medications affecting heart rate and blood sugar levels.
