Key takeaways:
Metoprolol tartrate (Lopressor) is a beta blocker medication that's FDA-approved for high blood pressure, chest pain, and after a heart attack. It comes as an oral tablet and intravenous (IV) injection.
Your metoprolol dosage depends on what you’re taking it for. It’s usually given once or twice a day. It’s usually started at a lower dose and raised weekly if needed.
Metoprolol is available as a brand-name medication and lower-cost generic. You can find generic metoprolol at an affordable price at certain pharmacies with a free GoodRx discount.
Metoprolol tartrate (Lopressor) is part of a group of medications called beta blockers. It’s an oral tablet that’s FDA-approved to treat high blood pressure and chest pain (angina). It’s also used after a heart attack to lower the risk of death.
Taking metoprolol correctly is critical to getting the most out of this medication. The recommendations given in this guide are from the manufacturer of metoprolol. But you should always take the dose recommended by your healthcare provider.
The metoprolol dosage for adults varies depending on why you’re taking it. But in general, metoprolol should be taken with a full glass of water. It should be taken at the same time each day and with a meal (or right after a meal).
For high blood pressure, the typical metoprolol dosage is between 100 mg to 450 mg total per day. Doses may be taken once or twice a day. Your healthcare provider will usually have you start at 100 mg and raise the dose weekly as needed.
Lower doses, like 100 mg, may not last all day if given as one dose. So, lower doses especially may need to be taken twice a day.
Though beta-blockers aren’t usually first-choice medications for high blood pressure, they’re used in certain situations. This includes people with high blood pressure who’ve recently had a heart attack or heart failure.
For high blood pressure, metoprolol is typically combined with another blood pressure lowering medication such as a diuretic.
The typical starting dose for chronic chest pain is 50 mg twice daily. Your healthcare provider may suggest for you to raise your weekly dosage depending on how you respond. The maximum dose is usually 400 mg per day.
Intravenous (IV) metoprolol may be given to someone that arrives in the hospital and is suspected of having a heart attack.
After this first IV treatment, oral metoprolol tablets are usually continued in the hospital and at home. This combination of IV and oral metoprolol is known to prevent a future heart attack, cardiac arrest, and death.
After the first IV dose of metoprolol, you may go home with an oral dose of 100 mg twice daily. But how long you’ll take metoprolol after a heart attack depends on a few factors. Talk to your healthcare provider about how long you’ll need metoprolol.
If you have existing liver problems, your healthcare provider may start metoprolol at a lower dose than usual. This is because metoprolol is broken down by your liver.
If your liver isn’t working as well as it could, it can build up in the body and cause side effects. So, starting at a lower dose can help prevent this.
Make sure to discuss your medical history with your healthcare provider before starting metoprolol. This includes any medical conditions you have and all the medications you take.
If you take certain medications or substances that interact with metoprolol, you may need a lower metoprolol dosage.
If you miss a dose of metoprolol, take it as soon as you remember. But if it’s almost time for your next dose, just take the next scheduled dose. Don’t double up on doses at any point. Taking two doses at once can raise your risk of side effects like a slow heart rate, shortness of breath, or dizziness.
If you feel that metoprolol isn’t working for you or it’s causing side effects, talk to your healthcare provider.
But, you shouldn’t stop metoprolol suddenly. It’s often necessary to lower the dose gradually before stopping it.
Taking too much metoprolol can raise your risk of side effects. This includes a dangerously slow heart rate and extremely low blood pressure. It can even lead to your heart not working. Low blood sugar can also be a sign of too much metoprolol.
If you or someone you know has taken too much metoprolol, get urgent medical help or call Poison Control at 1-800-222-1222.
Metoprolol is available as both a brand-name and lower-cost generic medication. GoodRx can help you save over 30% off the average retail price of the generic version. Generic metoprolol tablets at certain pharmacies are as low as $5.96 with a free GoodRx discount.
Your metoprolol dosage depends on what you’re treating. And if you have liver problems, you may be started on a lower dose.
Regardless of your dose, you should take it with a full glass of water at the same time(s) each day. If you miss a dose, take it as soon as you remember unless it’s close to your next dose.
And in this case, just skip your missed dose and return to your regular dosing schedule. Never take two doses at one time.
Bockstall, K., et al. (2017). How long should we continue beta-blockers after MI? American College of Cardiology.
DailyMed. (2022). Metoprolol tartrate.
Khalid, M. M., et al. (2022). Beta-blocker toxicity. StatPearls.
O’Gara, P. T., et al. (2013). 2013 ACCF/AHA guideline for the management of ST-evaluation myocardial infarction: A report of the American College of Cardiology Foundation/ American Heart Association Task Force on practice guidelines. Journal of the American College of Cardiology.
Preferred Pharmaceuticals Inc. (2022). Metoprolol tartrate [package insert].
Whelton, P. K., et al. (2017). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: Executive summary. Hypertension.
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