Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Losartan (Cozaar) and sotalol (Betapace) are both prescription medications, but they are used for different health conditions and belong to different drug classes. Losartan is an angiotensin II receptor blocker (ARB) primarily used to lower blood pressure and protect against stroke, as well as to slow down kidney problems in people with diabetes. It is taken once daily and is available in a lower-cost generic form. On the other hand, sotalol is a non-selective beta blocker and potassium channel blocker used to treat and prevent certain heart rhythm problems like atrial fibrillation. Sotalol is typically taken twice a day and also comes in a generic form. Unlike losartan, starting sotalol usually requires a hospital stay for monitoring due to the risk of serious side effects like abnormal heart rhythms. While losartan mainly affects blood pressure, sotalol works by slowing down electrical activity in the heart to manage arrhythmias. Both medications can cause dizziness and fatigue, but sotalol has additional risks like breathing problems and low blood sugar levels, especially in people with diabetes.
Losartan (Cozaar)
Sotalol (Betapace)
Losartan (Cozaar)
Sotalol (Betapace)
Summary of Losartan vs. Betapace
Summary for ARB
Prescription only
Losartan, also known by the brand name Cozaar, is a first-choice medication that's used to lower blood pressure. It's also shown to protect against stroke in certain people. In addition, this medication can slow down the worsening of kidney problems in certain people with diabetes. Losartan (Cozaar) belongs to the drug class called angiotensin II receptor blockers (ARBs). This medication is taken by mouth once daily and is available as a lower-cost generic. Side effects can include dizziness, fatigue, and upper respiratory infections.
Summary for Antiarrhythmic
Prescription only
Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.