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Hydrochlorothiazide vs. Ziac

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Hydrochlorothiazide (generic name) and Ziac (bisoprolol/hydrochlorothiazide) are both medications used to lower blood pressure, but they belong to different drug classes. Hydrochlorothiazide is a thiazide diuretic, also known as a water pill, that helps you urinate more to remove extra fluid and certain electrolytes from your body. Ziac, on the other hand, is a combination of two medications: bisoprolol, a cardioselective beta blocker, and hydrochlorothiazide. Bisoprolol works by slowing down your heart rate and lowering blood pressure, while hydrochlorothiazide in Ziac has the same diuretic effect as when taken alone. Hydrochlorothiazide is typically taken once or twice daily, whereas Ziac is taken once daily. Both medications can cause dizziness and increased urination. Ziac may also cause tiredness and has a specific warning about stopping it suddenly due to the risk of serious heart problems. Additionally, both medications are available in generic forms, which can help save you money.

Prices with our coupons for Hydrochlorothiazide vs. Ziac

Price Card Drug Icon
Hydrochlorothiazide30 tablets / 25mg
$4.00$4.00
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Price Card Drug Icon
Bisoprolol/HCTZ90 tablets / 5mg/6.25mg
$35.27$228.11
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