Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Tenoretic (atenolol/chlorthalidone) and metoprolol/hydrochlorothiazide are both combination medications used to lower blood pressure, but they have some differences. Tenoretic combines atenolol, a cardioselective beta blocker, with chlorthalidone, a thiazide-like diuretic. Metoprolol/hydrochlorothiazide combines metoprolol tartrate, another cardioselective beta blocker, with hydrochlorothiazide, a thiazide diuretic. Tenoretic is typically taken once daily, while metoprolol/hydrochlorothiazide can be taken once or twice daily with food. Both medications can cause dizziness, tiredness, nausea, and slow heartbeat. Additionally, Tenoretic is not safe for use during pregnancy or breastfeeding, while metoprolol/hydrochlorothiazide has similar warnings but also includes a risk of eye problems and lupus. Both medications should not be stopped suddenly due to the risk of heart problems.
Tenoretic (atenolol / chlorthalidone)
Metoprolol/hydrochlorothiazide
Tenoretic (atenolol / chlorthalidone)
Metoprolol/hydrochlorothiazide
Summary of Tenoretic vs. Lopressor HCT
Summary for Beta blocker / Diuretic (water pill)
Prescription only
Tenoretic (atenolol / chlorthalidone) is used to lower blood pressure in adults. It's a combination of two types of blood pressure medications: a beta blocker (atenolol) and a diuretic (chlorthalidone). The tablet is taken by mouth once daily. Side effects, like dizziness and tiredness, are usually mild and they get better over time. Tenoretic (atenolol / chlorthalidone) is available as a brand-name and generic medication.
Summary for Beta blocker / Thiazide diuretic
Prescription only
Metoprolol/hydrochlorothiazide is a combination medication that's used to lower blood pressure in adults. It contains a beta blocker (metoprolol tartrate) that slows down the heart and a thiazide diuretic (hydrochlorothiazide) that removes extra fluids through your kidneys. Metoprolol/hydrochlorothiazide is taken by mouth, typically once or twice daily with food. Some of the more common side effects of this medication include dizziness and tiredness. The brand name, Lopressor HCT, is no longer available.