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Tenoretic vs. Lopressor HCT

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tenoretic (atenolol/chlorthalidone) and metoprolol/hydrochlorothiazide are both combination medications used to lower blood pressure, but they have some differences. Tenoretic combines atenolol, a cardioselective beta blocker, with chlorthalidone, a thiazide-like diuretic. Metoprolol/hydrochlorothiazide combines metoprolol tartrate, another cardioselective beta blocker, with hydrochlorothiazide, a thiazide diuretic. Tenoretic is typically taken once daily, while metoprolol/hydrochlorothiazide can be taken once or twice daily with food. Both medications can cause dizziness, tiredness, nausea, and slow heartbeat. Additionally, Tenoretic is not safe for use during pregnancy or breastfeeding, while metoprolol/hydrochlorothiazide has similar warnings but also includes a risk of eye problems and lupus. Both medications should not be stopped suddenly due to the risk of heart problems.

Tenoretic

(atenolol / chlorthalidone)

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Metoprolol/hydrochlorothiazide

 

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Summary for Tenoretic

Prescription only

Tenoretic (atenolol / chlorthalidone) is used to lower blood pressure in adults. It's a combination of two types of blood pressure medications: a beta blocker (atenolol) and a diuretic (chlorthalidone). The tablet is taken by mouth once daily. Side effects, like dizziness and tiredness, are usually mild and they get better over time. Tenoretic (atenolol / chlorthalidone) is available as a brand-name and generic medication.

Indications for Tenoretic

Pros and Cons for Tenoretic

Pros

  • Combines two medications into one pill to help lower blood pressure better
  • Only need to take once a day
  • Can take with or without food
  • Gets rid of extra fluids in your body

Cons

  • Might make you urinate more often
  • Comes in fixed doses, which makes it hard to adjust the dose if needed
  • Not safe if you're pregnant or breastfeeding
  • Might cause an allergic reaction if you have a sulfa allergy

Common Side Effects for Tenoretic

Atenolol:

  • Dizziness
  • Tiredness
  • Nausea
  • Slow heartbeat

Chlorthalidone:

  • Dizziness when standing up too quickly
  • Stomach irritation or cramps
  • Nausea
  • Constipation

Warnings for Tenoretic

  • Risk of heart problems after stopping Tenoretic (atenolol / chlorthalidone) suddenly
  • Risk of heart failure
  • Risk of heart block when taken with calcium channel blockers
  • Caution use in people with breathing problems
  • Kidney problems
  • Changes in fluids and electrolytes in the body
  • Hidden symptoms of low blood sugar
  • Hidden symptoms of overactive thyroid
  • Possible gout
  • Risk of harm to baby

Summary for Lopressor HCT

Prescription only

Metoprolol/hydrochlorothiazide is a combination medication that's used to lower blood pressure in adults. It contains a beta blocker (metoprolol tartrate) that slows down the heart and a thiazide diuretic (hydrochlorothiazide) that removes extra fluids through your kidneys. Metoprolol/hydrochlorothiazide is taken by mouth, typically once or twice daily with food. Some of the more common side effects of this medication include dizziness and tiredness. The brand name, Lopressor HCT, is no longer available.

Indications for Lopressor HCT

Pros and Cons for Lopressor HCT

Pros

  • Taken by mouth just once or twice daily
  • Lowers risk of heart attack and stroke
  • Combines 2 medications into 1 pill for convenience

Cons

  • Can make you urinate more often
  • Stopping suddenly can raise risk of chest pain and heart attack
  • Fixed dosing, so not as easy to adjust the dose (compared to taking each medication separately)

Common Side Effects for Lopressor HCT

  • Tiredness
  • Dizziness
  • Weakness
  • Sun sensitivity

Note: Side effects listed are from people who took metoprolol tartrate or hydrochlorothiazide in clinical studies.

Warnings for Lopressor HCT

  • Risk of chest pain and heart attack
  • Heart failure
  • Risk of difficulty breathing
  • Slow heart rate
  • Greater risk during surgery
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of overactive thyroid
  • Fluid, electrolyte, and kidney problems
  • Eye problems
  • Lupus
  • Serious allergic reactions

Prices with our coupons for Tenoretic vs. Lopressor HCT

Price Card Drug Icon
Atenolol/Chlorthalidone90 tablets / 50mg/25mg
$38.95$155.99
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Price Card Drug Icon
Metoprolol/HCTZ90 tablets / 50mg/25mg
$32.28$129.60
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