Compare Propranolol vs. Hydrochlorothiazide

Propranolol (Inderal LA, Inderal XL, Innopran XL) and hydrochlorothiazide (Microzide) are both prescription medications used to treat high blood pressure, but they belong to different drug classes and work in different ways. Propranolol is a beta blocker that slows down your heart rate and relaxes blood vessels, which can also help with conditions like chest pain, migraines, and tremors. On the other hand, hydrochlorothiazide is a diuretic, or water pill, that helps you get rid of extra fluid and certain electrolytes through urination, which also reduces swelling from conditions like heart failure and kidney problems. Propranolol is available in both immediate-release and extended-release forms, while hydrochlorothiazide is typically taken once or twice daily. Common side effects of propranolol include dizziness, tiredness, and weakness, whereas hydrochlorothiazide can cause dizziness, increased urination, and sensitivity to sunlight. Additionally, propranolol can hide symptoms of low blood sugar, which is important for people with diabetes, while hydrochlorothiazide can affect your electrolyte balance and may raise blood sugar levels. Both medications have generic versions available, making them more affordable options.