Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Propranolol (Inderal LA, Inderal XL, Innopran XL) and Fioricet (butalbital/acetaminophen/caffeine) are both prescription medications, but they serve different purposes and belong to different drug classes. Propranolol is a non-selective beta blocker used to treat conditions like high blood pressure, chronic chest pain, and migraines. It works by slowing down your heart rate and relaxing blood vessels. On the other hand, Fioricet is a combination medication used to treat tension headaches. It contains a barbiturate (butalbital), an analgesic (acetaminophen), and caffeine, which work together to relieve headache pain. Propranolol is typically taken 1 to 4 times daily, depending on whether you use the immediate-release or extended-release form, while Fioricet is taken every 4 hours as needed, but no more than 6 capsules in 24 hours. Propranolol can cause side effects like dizziness and tiredness, whereas Fioricet can cause drowsiness, dizziness, and has a risk of misuse and dependence. Additionally, Fioricet is controlled in some states due to its potential for habit formation, while propranolol is not a controlled substance.
Summary for Barbiturate / Analgesic / Adenosine antagonist
Prescription only
Fioricet is a combination medication containing butalbital, acetaminophen, and caffeine. It's taken by mouth as needed, typically every 4 hours, to treat tension headaches. But it's not a first-choice option because it can become habit-forming and can worsen headaches if taken too frequently. In addition, Fioricet can cause side effects, such as sleepiness and dizziness. It's available as pills and an oral syrup.