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Compare Tegretol vs. Propranolol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carbamazepine (Tegretol, Equetro) and propranolol (Inderal, Innopran XL) are both prescription medications, but they treat different conditions and belong to different drug classes. Carbamazepine is an antiepileptic used to manage seizures, trigeminal neuralgia, and bipolar I disorder (Equetro brand only). It works by blocking sodium channels in the brain. Propranolol, on the other hand, is a non-selective beta blocker that treats high blood pressure, chest pain, migraines, and tremors by slowing down the heart rate and relaxing blood vessels. Carbamazepine is available in various forms, including pills and liquid, and can be taken multiple times a day, while Propranolol is available in immediate-release and extended-release forms, with the latter taken once daily. Common side effects of carbamazepine include dizziness and sleepiness, whereas propranolol often causes tiredness and dizziness. Additionally, carbamazepine can cause serious skin reactions and low blood cell counts, while propranolol can hide symptoms of low blood sugar and is not safe for people with asthma.

Carbamazepine (Tegretol)
Propranolol
Carbamazepine (Tegretol)
Propranolol
Summary of Tegretol vs. Propranolol
Summary for Antiepileptic
Prescription only
Carbamazepine (Tegretol) is an antiseizure medication used to treat different kinds of seizures. It can also help with trigeminal neuralgia, a type of facial nerve pain. Brand name Equetro is the only formulation that's approved to treat bipolar I disorder. Carbamazepine (Tegretol) available as pills and a liquid. Depending on formulation you take and what medical condition you have, carbamazepine (Tegretol) is taken by mouth 1 to 4 times per day. Common side effects include sleepiness, dizziness, and stomach upset.
Summary for Beta blocker
Prescription only
Propranolol is a non-selective beta blocker. It helps with a range of medical conditions, including high blood pressure, tremors, and migraine prevention. Sometimes, providers prescribe propranolol off-label to ease performance anxiety. You take this medication by mouth, typically 1 to 4 times daily, depending on if you're taking the immediate-release (IR) or extended-release (ER) medication. Keep in mind the IR and ER versions don't treat the same medical conditions. Some of the more common side effects of propranolol include dizziness, tiredness, or weakness.
Indications of Tegretol vs. Propranolol
Indications for

•Partial-onset seizures

•Generalized tonic-clonic seizures

•Mixed seizure patterns

•Trigeminal neuralgia (facial nerve pain)

•Bipolar I disorder - Equetro brand only

Indications for

•High blood pressure

•Chronic chest pain

•Migraine

•Hypertrophic subaortic stenosis

•Atrial fibrillation (A.Fib)

•Heart protection after a heart attack

•Tremors

•Pheochromocytoma (a rare tumor of the adrenal gland)
Pros and Cons of Tegretol vs. Propranolol
Pros and Const for Antiepileptic
Pros

•Works well for different types of seizures and trigeminal neuralgia (facial nerve pain)

•Helps stabilize mood in people with bipolar disorder (Equetro brand only)

•Available as a lower-cost generic

•Comes in many dosage forms (e.g., chewable tablets, oral pills, liquid form) for people who have difficulty swallowing pills

Cons

•Might need to take the immediate-release form of the medication up to 4 times a day

•Can cause a lot of side effects

•Might require routine blood testing while taking the medication to see how it's affecting your body

•Can make hormonal birth control not work as well

Pros and Const for Beta blocker
Pros

•Taken by mouth

•Long-acting version only needs to be taken once a day

•Oral solution might be a good option for people who can't swallow pills

•Available as lower-cost generics

Cons

•Not safe for people with asthma or certain serious heart conditions

•Can hide many recognizable symptoms of low blood sugar, such as fast heart beat or tremors, which might prevent timely treatment

•Missing doses or suddenly stopping propranolol can raise your risk of heart attacks
Common Side Effects of Tegretol vs. Propranolol
Common Side Effects for

•Dizziness (44%)

•Sleepiness (32%)

•Nausea (29%)

•Vomiting (18%)

•Difficulty walking or keeping balance (15%)

•Constipation (10%)

•Itching (8%)

•Dry mouth (8%)

•Weakness (8%)

•Rash (7%)

•Blurry vision (6%)

•Speech problems (6%)

Common Side Effects for

•Dizziness

•Tiredness

•Feeling weak
Warnings of Tegretol vs. Propranolol
Common Side Effects for

•Severe skin reactions

•Low blood cell counts

•Severe allergic reactions

•Suicidal thoughts or behavior

•Harm to unborn babies

•Withdrawal

•Difficulty with speech, concentration, and movement

•Liver problems

•Low sodium levels

•High eye pressure

•Heart block (heart rhythm problems)

Common Side Effects for

•Worsening of chest pain or heart attack

•Higher risk or worsening of heart failure

•Hidden symptoms of low blood sugar

•Hidden symptoms of overactive thyroid

•Trouble breathing (bronchospastic disease)

•Serious skin reactions

•Greater risk during surgery
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Compare Tegretol vs. Propranolol

Key takeaways

Summary of Tegretol vs. Propranolol

Indications of Tegretol vs. Propranolol

Pros and Cons of Tegretol vs. Propranolol

Common Side Effects of Tegretol vs. Propranolol

Warnings of Tegretol vs. Propranolol

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