Key takeaways
Propranolol (Inderal LA, Inderal XL, Innopran XL) and venlafaxine (Effexor XR) are both prescription medications that can be used to treat anxiety, although propranolol is used off-label for performance anxiety. Propranolol is a non-selective beta blocker used for a number of health conditions, including high blood pressure, tremor, and migraine prevention. It is available in both immediate-release and extended-release forms, with dosing varying based on the condition being treated. Common side effects include dizziness, tiredness, and weakness. Venlafaxine, on the other hand, is a serotonin and norepinephrine reuptake inhibitor (SNRI) used for mental health conditions such as depression, generalized anxiety disorder, social anxiety disorder, and panic disorder. It comes in immediate-release and extended-release forms. Common venlafaxine side effects include nausea, weight changes, and sexual problems. Venlafaxine can interact with many medications and may cause withdrawal symptoms if stopped suddenly. Both medications are available as a lower-cost generic. Propranolol is not recommended for people with asthma or certain heart conditions, while venlafaxine may raise blood pressure and can increase the risk of serotonin syndrome.
