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Topamax vs. Baclofen

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

• Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
• Migraine prevention in people 12 years and older

• "Pins and needles" feeling
• Sleepiness
• Dizziness
• Fatigue
• Low appetite
• Weight loss
• Nervousness
• Depression
• Trouble concentrating
• Trouble remembering things
• Trouble sleeping
• Trouble moving or keeping balance
• Fever
• Mood changes
• Change in taste

• Vision problems
• High body temperature and trouble sweating
• Too much acid in the blood (metabolic acidosis)
• Changes in mood and risk of suicidal thoughts or behavior
• Problems with memory, speech, or coordination
• Sleepiness, tiredness, and lower concentration
• High ammonia levels in the blood
• Serious skin reactions
• Kidney stones
• Risk of seizures if you stop the medication suddenly
• Bone or growth problems in children
• Interaction with other medications
• Harm to an unborn baby

Baclofen is a muscle relaxer. It's used to treat muscle spasms from multiple sclerosis or spinal cord injuries in adults and children ages 12 years and older. This medication is taken by mouth, typically 3 times a day. Baclofen comes as tablets, as well as oral solutions (including brand names Ozobax DS and Fleqsuvy) and dissolvable granules (brand name Lyvispah) for people who've trouble swallowing tablets. Side effects of baclofen include sleepiness, dizziness, and nausea. If you stop this medication too suddenly, you might experience withdrawal symptoms.

• Muscle spasms from multiple sclerosis or spinal cord injuries in people ages 12 years and older

• Sleepiness (up to 63%)
• Dizziness (up to 15%)
• Weakness (up to 15%)
• Nausea (up to 12%)
• Confusion (up to 11%)

• Withdrawal symptoms
• Extreme sleepiness or dizziness
• Worsening of other health conditions
• Don't take during pregnancy