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Compare Topamax vs. Dilantin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Topiramate (Topamax, Qudexy XR, Trokendi XR, Eprontia) and phenytoin (Dilantin) are both antiepileptic medications used to treat seizures, but they have some key differences. Topiramate can be used alone or with other medications to treat various types of seizures and to prevent migraines, while phenytoin is only used for treating and preventing seizures. Topiramate is available in multiple forms, including tablets, capsules, and a liquid solution, and can be taken once or twice daily. In contrast, phenytoin is available as capsules, chewable tablets, and liquid, and typically requires multiple doses per day. Both medications can cause serious side effects, with topiramate increasing the risk for causing kidney stones and vision problems and phenytoin can lead to heart problems and liver damage. Additionally, both medications can affect birth control effectiveness and pose risks during pregnancy, including birth defects. Your healthcare professional may order periodic tests to measure the blood levels of these medications and monitor potential side effects.

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