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Compare Myrbetriq vs. Ditropan XL

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Myrbetriq (mirabegron) and oxybutynin ER (Ditropan XL) are both used to treat overactive bladder (OAB), but they work in different ways and have different side effects. Myrbetriq is a beta-3 adrenergic agonist that helps your bladder relax to hold more urine, while oxybutynin is an anticholinergic that reduces bladder muscle spasms. Myrbetriq is taken once daily and is available only in oral form, whereas oxybutynin comes in multiple forms, including tablets, patches, and gels. Myrbetriq can cause high blood pressure and urinary tract infections, while oxybutynin commonly causes dry mouth, dizziness, and constipation. Oxybutynin might not be the best choice for older adults due to its higher risk of side effects like drowsiness and confusion. Additionally, Myrbetriq does not have a generic version available, but oxybutynin does.

drug combination

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  • Myrbetriq (mirabegron)
    Oxybutynin
  • Myrbetriq (mirabegron)
    Oxybutynin

  • Summary of Myrbetriq vs. Ditropan XL

    Summary for Beta-3 adrenergic agonist
    Prescription only

    Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

    Summary for Urinary antispasmodic
    Prescription only

    Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

  • Indications of Myrbetriq vs. Ditropan XL

    Indications for
    •Overactive bladder (OAB) in adults
    •Neurogenic detrusor overactivity (NDO) in children ages 3 years and older
    Indications for
    •Overactive bladder
    •Incontinence in children due to a neurologic (brain) condition, such as spina bifida

  • Pros and Cons of Myrbetriq vs. Ditropan XL

    Pros and Const for Beta-3 adrenergic agonist
    Pros
    •Helps control sudden urges to urinate, leaks, and needing to go too often
    •Only taken once a day
    •Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
    •Might be safer for older adults than anticholinergics for overactive bladder
    Cons
    •Might raise your blood pressure
    •Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
    •Not recommended if you have severe kidney or liver problems
    Pros and Const for Urinary antispasmodic
    Pros
    •Works well to improve symptoms of OAB
    •Available as a convenient, once-daily tablet (Ditropan XL)
    •Can be used in children as young as 5 years old
    •Available as an oral liquid, good for people who have trouble swallowing tablets
    Cons
    •Commonly causes dry mouth as a side effect
    •Higher risk of side effects in people age 65 and older
    •Can cause dizziness and drowsiness
    •Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines

  • Common Side Effects of Myrbetriq vs. Ditropan XL

    Common Side Effects for

    Adults:

    •High blood pressure (8-11%)
    •Common cold symptoms (4%)
    •Urinary tract infection (3-4%)
    •Headache (2-3%)
    •Constipation (2%)
    •Upper respiratory tract infection (2%)

    Children:

    •Urinary tract infection (24%)
    •Common cold symptoms (6%)
    •Constipation (5%)
    •Headache (4%)
    •Nausea (2%)
    Common Side Effects for
    •Dry mouth (up to 71%)
    •Dizziness (up to 17%)
    •Constipation (up to 15%)
    •Sleepiness (up to 14%)
    •Nausea (up to 12%)
    •Blurry vision (up to 10%)

  • Warnings of Myrbetriq vs. Ditropan XL

    Common Side Effects for
    •High blood pressure
    •Risk of having trouble fully emptying the bladder in certain people
    •Unusual swelling of the face, lips, or throat (angioedema)
    •Interactions with other medications
    Common Side Effects for
    •Swelling of face, lips, tongue (angioedema)
    •Hallucinations, drowsiness, and confusion
    •Worsening of other conditions
    •Heat exhaustion

  • Prices with our coupons for Myrbetriq vs. Ditropan XL

    Learn more about Myrbetriq
    Learn more about Oxybutynin

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