Key takeaways
Myrbetriq (mirabegron) and oxybutynin ER (Ditropan XL) are both used to treat overactive bladder (OAB), but they work in different ways and have different side effects. Myrbetriq is a beta-3 adrenergic agonist that helps your bladder relax to hold more urine, while oxybutynin ER is an anticholinergic that reduces bladder muscle spasms. Myrbetriq is taken once daily and is only available in oral form, whereas oxybutynin ER can be taken as a tablet, patch, or gel, with the tablet form also taken once daily. Common side effects of Myrbetriq include high blood pressure and urinary tract infections, while oxybutynin ER often causes dry mouth, dizziness, and constipation. Myrbetriq does not have a generic version, but oxybutynin ER does. Additionally, oxybutynin ER may not be suitable for older adults due to a higher risk of side effects like drowsiness and confusion.
