Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Myrbetriq vs. Vesicare

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Myrbetriq (mirabegron) and Vesicare (solifenacin) are both used to treat overactive bladder (OAB), but they work in different ways and belong to different drug classes. Myrbetriq (mirabegron) is a beta-3 adrenergic agonist that helps your bladder relax so it can hold more urine, while Vesicare (solifenacin) is an anticholinergic and antimuscarinic that reduces bladder muscle spasms. Myrbetriq is available only as a brand name and can be taken by adults and children over 3 years old, whereas Vesicare has a generic version and can be used by adults and a liquid version for children over 2 years old. Common side effects of Myrbetriq include high blood pressure and urinary tract infections, while Vesicare often causes dry mouth and constipation. Myrbetriq is generally taken once a day and can be combined with Vesicare for better results. Vesicare should not be used if you have untreated narrow-angle glaucoma or certain gastrointestinal conditions. Both medications can cause serious side effects like angioedema, but Vesicare also carries a risk of heart rhythm problems and heat exhaustion.

  • Myrbetriq (mirabegron)
    Solifenacin (Vesicare)
  • Myrbetriq (mirabegron)
    Solifenacin (Vesicare)

  • Summary of Myrbetriq vs. Vesicare

    Summary for Beta-3 adrenergic agonist
    Prescription only

    Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

    Summary for Anticholinergic
    Prescription only

    Solifenacin succinate, also known by the brand name Vesicare, is an anticholinergic medication that's used to treating certain bladder problems. The brand-name and generic tablets help treat overactive bladder in adults. A liquid suspension under the brand name Vesicare LS is also available for children with neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem). This medication is taken by mouth once per day. The most common side effects are dry mouth and constipation.

  • Indications of Myrbetriq vs. Vesicare

    Indications for
    •Overactive bladder (OAB) in adults
    •Neurogenic detrusor overactivity (NDO) in children ages 3 years and older
    Indications for
    •Overactive bladder in adults - tablets only
    •Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only

  • Pros and Cons of Myrbetriq vs. Vesicare

    Pros and Const for Beta-3 adrenergic agonist
    Pros
    •Helps control sudden urges to urinate, leaks, and needing to go too often
    •Only taken once a day
    •Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
    •Might be safer for older adults than anticholinergics for overactive bladder
    Cons
    •Might raise your blood pressure
    •Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
    •Not recommended if you have severe kidney or liver problems
    Pros and Const for Anticholinergic
    Pros
    •Only taken once per day, with or without food
    •Comes as a tablet and a liquid suspension
    •Liquid suspension available for children as young as 2 years old
    Cons
    •Commonly causes dry mouth
    •Liquid suspension is brand name only
    •Not a good option for people who have trouble urinating or certain gut problems

  • Common Side Effects of Myrbetriq vs. Vesicare

    Common Side Effects for

    Adults:

    •High blood pressure (8-11%)
    •Common cold symptoms (4%)
    •Urinary tract infection (3-4%)
    •Headache (2-3%)
    •Constipation (2%)
    •Upper respiratory tract infection (2%)

    Children:

    •Urinary tract infection (24%)
    •Common cold symptoms (6%)
    •Constipation (5%)
    •Headache (4%)
    •Nausea (2%)
    Common Side Effects for
    •Dry mouth (up to 28% in adults, 8% in children)
    •Constipation (up to 13% in adults, 3% in children)

  • Warnings of Myrbetriq vs. Vesicare

    Common Side Effects for
    •High blood pressure
    •Risk of having trouble fully emptying the bladder in certain people
    •Unusual swelling of the face, lips, or throat (angioedema)
    •Interactions with other medications
    Common Side Effects for
    •Swelling of the face and possible breathing problems (angioedema)
    •Side effects related to the nervous system
    •Caution in people with digestive system problems
    •Caution in people with glaucoma
    •QT prolongation (heart rhythm problem)

  • Prices with our coupons for Myrbetriq vs. Vesicare

    Learn more about Myrbetriq
    Learn more about Solifenacin

Compare other Overactive Bladder drugs

Enablex vs MyrbetriqGemtesa vs MyrbetriqMyrbetriq vs DetrolMyrbetriq vs DitropanMyrbetriq vs FlomaxMyrbetriq vs OxybutyninMyrbetriq vs SancturaMyrbetriq vs ToviazMyrbetriq vs VesicarePropranolol vs MyrbetriqTopamax vs MyrbetriqCogentin vs PropranololDantrium vs PropranololDilantin vs PropranololElavil vs PropranololLamictal vs PropranololNeurontin vs PropranololPropranolol vs BaclofenPropranolol vs BisoprololPropranolol vs BystolicPropranolol vs CafergotPropranolol vs CoregPropranolol vs DepakotePropranolol vs DetrolPropranolol vs EffexorPropranolol vs FioricetPropranolol vs HydrochlorothiazidePropranolol vs KeppraPropranolol vs LisinoprilPropranolol vs Losartan
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.