Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vibegron (Gemtesa) and mirabegron (Myrbetriq) are both medications used to treat overactive bladder (OAB) in adults, and they belong to the same drug class, beta-3 adrenergic agonists. However, they have some differences. Vibegron is only approved for adults, while mirabegron can also be used in children ages 3 years and older for neurogenic detrusor overactivity (NDO). Vibegron is taken as a 75 mg tablet once daily, whereas mirabegron is available in tablet form and as as an oral liquid solution, with dosing that can vary based on age and condition. Neither medication has a generic version available. Common side effects of vibegron include headache and cold symptoms, while mirabegron can cause high blood pressure and urinary tract infections. Additionally, mirabegron may interact with other medications like digoxin (Lanoxin) and warfarin (Coumadin, Jantoven), while vibegron is only known to interact with digoxin. Both medications can cause angioedema, a serious allergic reaction, but mirabegron has a specific warning about raising blood pressure.
Gemtesa
Myrbetriq (mirabegron)
Gemtesa
Myrbetriq (mirabegron)
Summary of Gemtesa vs. Myrbetriq
Summary for Beta-3 adrenergic agonist
Prescription only
Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.
Summary for Beta-3 adrenergic agonist
Prescription only
Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.