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Compare Gemtesa vs. Solifenacin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Vibegron (Gemtesa) and solifenacin (Vesicare) are both medications used to treat overactive bladder (OAB) in adults. However, they belong to different medication classes. Vibegron is a beta-3 adrenergic agonist, while solifenacin is an anticholinergic. Vibegron is taken as a 75 mg tablet once daily, and there is no generic version available. Solifenacin is available in both tablet and liquid forms, with the tablet dose ranging from 5 mg to 10 mg daily, and a generic version is available. Vibegron can cause headaches and cold symptoms, while solifenacin commonly causes dry mouth and constipation. Solifenacin also has more potential side effects, such as dizziness and blurry vision, and it can interact with other medications that affect the nervous system. Vibegron is not recommended for people with severe liver or kidney problems, while solifenacin should be avoided by those with certain eye, stomach, or urinary conditions.

  • Gemtesa
    Solifenacin (Vesicare)
  • Gemtesa
    Solifenacin (Vesicare)

  • Summary of Gemtesa vs. Solifenacin

    Summary for Beta-3 adrenergic agonist
    Prescription only

    Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.

    Summary for Anticholinergic
    Prescription only

    Solifenacin succinate, also known by the brand name Vesicare, is an anticholinergic medication that's used to treating certain bladder problems. The brand-name and generic tablets help treat overactive bladder in adults. A liquid suspension under the brand name Vesicare LS is also available for children with neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem). This medication is taken by mouth once per day. The most common side effects are dry mouth and constipation.

  • Indications of Gemtesa vs. Solifenacin

    Indications for
    •Overactive bladder (OAB)
    •Overactive bladder in people who are taking medications for benign prostatic hyperplasia (BPH)
    Indications for
    •Overactive bladder in adults - tablets only
    •Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only

  • Pros and Cons of Gemtesa vs. Solifenacin

    Pros and Const for Beta-3 adrenergic agonist
    Pros
    •A first-choice option for overactive bladder
    •Can take with anticholinergics for OAB, if needed
    •Tablets are crushable if you have trouble swallowing pills
    Cons
    •Can take several weeks to see improvement in your symptoms
    •Not recommended for people with severe liver or kidney problems
    •Hasn't been studied in children
    Pros and Const for Anticholinergic
    Pros
    •Only taken once per day, with or without food
    •Comes as a tablet and a liquid suspension
    •Liquid suspension available for children as young as 2 years old
    Cons
    •Commonly causes dry mouth
    •Liquid suspension is brand name only
    •Not a good option for people who have trouble urinating or certain gut problems

  • Common Side Effects of Gemtesa vs. Solifenacin

    Common Side Effects for
    •Headache (4%)
    •Cold symptoms (3%)
    •Diarrhea (2%)
    •Nausea (2%)
    •Upper respiratory tract infection (2%)
    Common Side Effects for
    •Dry mouth (up to 28% in adults, 8% in children)
    •Constipation (up to 13% in adults, 3% in children)

  • Warnings of Gemtesa vs. Solifenacin

    Common Side Effects for
    •Angioedema (swelling of face, mouth, throat, or other organ)
    •Risk of difficulty emptying the bladder completely
    Common Side Effects for
    •Swelling of the face and possible breathing problems (angioedema)
    •Side effects related to the nervous system
    •Caution in people with digestive system problems
    •Caution in people with glaucoma
    •QT prolongation (heart rhythm problem)

  • Prices with our coupons for Gemtesa vs. Solifenacin

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    Learn more about Solifenacin

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