Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Oxybutynin (Ditropan XL) and tamsulosin (Flomax) are both prescription medications used to treat urinary issues, but they work in different ways and are used for different conditions. Oxybutynin is a urinary antispasmodic that treats overactive bladder (OAB) by relaxing bladder muscles, while tamsulosin is an alpha-1 blocker used for benign prostatic hyperplasia (BPH), which relaxes muscles in the prostate and bladder to ease urination. Oxybutynin is available in both short-acting and long-acting oral forms, as well as a patch and gel, and is taken 2 to 4 times a day or once daily for the extended-release form. Tamsulosin is taken once daily, 30 minutes after the same meal each day. Oxybutynin can cause side effects like dry mouth, constipation, and dizziness, while tamsulosin may lead to dizziness, headache, and abnormal ejaculation. Oxybutynin is not recommended for people with untreated narrow-angle glaucoma or certain stomach issues, whereas tamsulosin should be used cautiously in those with sulfa allergies or undergoing eye surgery.
Oxybutynin
Tamsulosin
Oxybutynin
Tamsulosin
Summary of Ditropan XL vs. Flomax
Summary for Urinary antispasmodic
Prescription only
Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.
Summary for Alpha-1 blocker
Prescription only
Tamsulosin is an alpha-1 blocker used to treat benign prostatic hyperplasia (BPH), also known as enlarged prostate. It works by relaxing the muscles in your prostate and bladder, making it easier to urinate. The medication comes as a capsule that you take once a day, usually 30 minutes after the same meal each day. Side effects include headache, dizziness, and abnormal ejaculation.
Indications of Ditropan XL vs. Flomax
Indications for
•Overactive bladder
•Incontinence in children due to a neurologic (brain) condition, such as spina bifida